|Isotope mass||18.0009380(6) u|
|Excess energy||873.431± 0.593 keV|
|Binding energy||137369.199± 0.593 keV|
|Decay mode||Decay energy|
|Positron emission||1.656 MeV|
Fluorine-18 is an important isotope in the radiopharmaceutical industry, and is primarily synthesized into fluorodeoxyglucose (FDG) for use in positron emission tomography (PET scans). It is substituted for hydrogen and used as a tracer in the scan. Its significance is due to both its short half-life and the emission of positrons when decaying. In the radiopharmaceutical industry, it is made using either a cyclotron or linear particle accelerator by bombarding oxygen-18 with hydrogen ions. Fluorine-18 is often used to substitute hydrogen due to similar steric properties. This may however be problematic in certain applications due to possible changes in molecule polarity.