Fletazepam

Fletazepam
	File:Fletazepam.svg
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Clinical data
Physiological data
Legal status
Pharmacokinetic data
Identifiers
	IUPAC name 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1,4-benzodiazepine;
CAS Number	34482-99-0;
PubChem Template:Abbreviation	36834;
Chemical and physical data
Formula	C17H13ClF4N2
Molar mass	356.745

Fletazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.^[1]

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam.^[2]

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References

↑ Barnett A, Goldstein J, Fiedler EP, Taber RI. The pharmacology of fletazepam, a centrally-acting muscle relaxant. Archives Internationales de Pharmacodynamie et de Therapie. 1974 Nov;212(1):164-74.
↑ Orio LC, Barnett A, Billard W. Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites. Life Sciences, 1984. (35):105-113.

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[1] Barnett A, Goldstein J, Fiedler EP, Taber RI. The pharmacology of fletazepam, a centrally-acting muscle relaxant. Archives Internationales de Pharmacodynamie et de Therapie. 1974 Nov;212(1):164-74.

[2] Orio LC, Barnett A, Billard W. Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites. Life Sciences, 1984. (35):105-113.

[1]

[2]

Fletazepam

References

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