Fever of unknown origin x ray

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X ray is a very easy and cost effective investigation while evaluating fever of unknown origin after laboratory investigations are done, the next best investigation of choice is X ray which may be helpful in some cases finding out cause of FUO. [1][2]

X Ray

  1. There may be air fluid level or cavities on chest x ray in case Tuberculosis is the cause of FUO.[3]
  2. Widened mediastinum may be seen on chest x ray in case Hodgkin lymphoma is the cause of FUO.
  3. Widened mediastinum is seen in case of giant cell temporal arteritis ( a cause of FUO) on chest x-ray is it can cause aortic dissection and aneurysm.
  4. Interstitial pattern is seen on chest x ray is seen in CMV or mycobacteria infection especially in people with HIV associated FUO.


  1. Mulders-Manders C, Simon A, Bleeker-Rovers C (2015). "Fever of unknown origin". Clin Med (Lond). 15 (3): 280–4. doi:10.7861/clinmedicine.15-3-280. PMC 4953114. PMID 26031980.
  2. Bleeker-Rovers CP, Vos FJ, de Kleijn EMHA, Mudde AH, Dofferhoff TSM, Richter C; et al. (2007). "A prospective multicenter study on fever of unknown origin: the yield of a structured diagnostic protocol". Medicine (Baltimore). 86 (1): 26–38. doi:10.1097/MD.0b013e31802fe858. PMID 17220753.
  3. Kaya A, Ergul N, Kaya SY, Kilic F, Yilmaz MH, Besirli K; et al. (2013). "The management and the diagnosis of fever of unknown origin". Expert Rev Anti Infect Ther. 11 (8): 805–15. doi:10.1586/14787210.2013.814436. PMID 23977936.

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