Famotidine (patient information)
Why this medication is prescribed
Prescription famotidine is used to to treat ulcers (sores on the lining of the stomach or small intestine); gastroesophageal reflux disease [GERD, a condition in which backward flow of acid from the stomach causes heartburn and injury of the esophagus (tube that connects the mouth and stomach)]; and conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome (tumors in the pancreas or small intestine that cause increased production of stomach acid). Over-the-counter famotidine is used to prevent and treat heartburn due to acid indigestion and sour stomach caused by eating or drinking certain foods or drinks. Famotidine is in a class of medications called H2 blockers. It works by decreasing the amount of acid made in the stomach.
How this medication should be used
Prescription famotidine comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken once daily at bedtime or two to four times a day. Over-the-counter famotidine comes as a tablet, a chewable tablet, and a capsule to take by mouth. It is usually taken once or twice a day. To prevent symptoms, it is taken 15 to 60 minutes before eating foods or drinking drinks that may cause heartburn. Follow the directions on your prescription or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take famotidine exactly as directed. Do not take more or less of it or take it more often or for a longer time than prescribed by your doctor.
Shake the liquid well for 5 to 10 seconds before each use to mix the medicine evenly.
Swallow the tablets and capsules with a full glass of water.
Thoroughly chew the chewable tablets before swallowing them. Swallow the chewed tablet with a full glass of water.
Do not take more than two tablets, capsules, or chewable tablets of over-the -counter famotidine in 24 hours and do not take over-the-counter famotidine for longer than 2 weeks unless your doctor tells you that you should. If symptoms of heartburn, acid indigestion, or sour stomach last longer than 2 weeks, stop taking over-the-counter famotidine and call your doctor.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Special precautions
Before taking famotidine:
- tell your doctor and pharmacist if you are allergic to famotidine, cimetidine (Tagamet), nizatidine (Axid), ranitidine (Zantac), or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any other medications for heartburn. Do not take over-the-counter famotidine with any other prescription or nonprescription medications for heartburn unless a doctor tells you that you should.
- tell your doctor if you have phenylketonuria (PKU, an inborn disease in which mental retardation develops if a specific diet is not followed), and if you have or have ever had trouble swallowing or kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking famotidine, call your doctor.
Special dietary instructions
Unless your doctor tells you otherwise, continue your normal diet.
What to do if you forget a dose
If you forget a dose of prescription famotidine, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Over-the-counter famotidine is usually taken as needed. If your doctor has told you to take over-the-counter famotidine regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Side effects
Minor side effects
Famotidine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache
- dizziness
- constipation
- diarrhea
- fussiness (in babies who take famotidine)
Severe side effects
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them call your doctor immediately:
- hives
- skin rash
- itching
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- hoarseness
- difficulty breathing or swallowing
Famotidine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].
Storage conditions needed for this medication
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not allow the liquid to freeze. Throw away any medication that is outdated or no longer needed, and throw away unused famotidine liquid after 30 days. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Other information
Keep all appointments with your doctor.
Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.
Brand names
- Pepcid®
- Pepcid® AC
- Pepcid® AC Gelcaps
- Pepcid® AC Maximum Strength
- Pepcid® Complete
- Pepcid® I.V.
- Pepcid® Premixed in Iso-osmotic Sodium Chloride Injection
- Pepcid® RPD