Ethcathinone

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Ethcathinone
Clinical data
Routes of
administration
oral, intranasal
Identifiers
E number{{#property:P628}}
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Chemical and physical data
FormulaC13H15NO
Molar mass177.3

Ethcathinone (also called Ethylpropion, N-ethylcathinone and 2-ethylaminopropiophenone), is a stimulant drug. It is an active metabolite of diethylcathinone and has a stimulant effect on the CNS.

Pharmacology

Ethcathinone is a methylphenidate-like DA/NE reuptake inhibitor (Rothman 2005). Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine. Chemically, it is the N-ethyl homologue of cathinone and dimethylcathinone.

Side effects

Severe
  • Insomnia
  • Pulmonary hypertension
  • Stroke
  • Psychosis
Cardiovascular
  • Tachycardia, hypertension, arrhythmia, chest pain
Ear, nose, and throat
  • Xerostomia, metallic taste
Endocrine
  • Changes in libido, gynecomastia, menstrual irregularities
Eye
  • Blurred vision
Gastrointestinal
  • Nausea/vomiting, constipation, abdominal cramps
Hematological
  • Bone marrow depression, agranulocytosis, leukopenia
Neurological
  • Tremor
Psychological
  • Euphoria, agitation, nervousness, restlessness, dizziness, anxiety, headache, mental depression, seizures
Skin
  • Rash, hives, alopecia, ecchymosis
Urogenital and reproductive
  • Changes in libido, impotence

See also

References



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