Ethamivan

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Ethamivan
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Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC12H17NO3
Molar mass223.268

Ethamivan (Analepticon) is a respiratory stimulant drug[1] related to nikethamide. It was mainly used in the treatment of barbiturate overdose[2] and chronic obstructive pulmonary disease,[3] but has now largely fallen into disuse. Some research suggests that it may have abuse potential.[4]




References

  1. Hirsh K, Wang SC. Respiratory stimulant effects of ethamivan and picrotoxin. Journal of Pharmacology and Experimental Therapeutics. 1975 May;193(2):657-63.
  2. Wheeldon PJ, Perry AW. The use of ethamivan in the treatment of barbiturate poisoning. Canadian Medical Association Journal. 1963 Jul 6;89:20-2.
  3. Sproule BJ, Jans RL, Breitkreutz H, Mahon W. Effects of ethamivan in patients with chronic respiratory disease. Canadian Medical Association Journal. 1964 Dec 5;91:1203-8.
  4. Ma C, Duan H, Zhang H, Xu Y, Zhou T. Studies on analytical method for 10 drugs of abuse in urine using HPLC. (Chinese) Yao Xue Xue Bao. 1998 Oct;33(10):764-7.

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