Enterococcus

(Redirected from Enterococcal Infection)
Jump to navigation Jump to search
Enterococcus
Enterococcus sp. infection in pulmonary tissue.
Enterococcus sp. infection in pulmonary tissue.
Scientific classification
Kingdom: Bacteria
Division: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Enterococcaceae
Genus: Enterococcus
(ex Thiercelin & Jouhaud 1903)
Schleifer & Kilpper-Bälz 1984
Species

E. avium
E. durans
E. faecalis
E. faecium
E. solitarius
etc.

WikiDoc Resources for Enterococcus

Articles

Most recent articles on Enterococcus

Most cited articles on Enterococcus

Review articles on Enterococcus

Articles on Enterococcus in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Enterococcus

Images of Enterococcus

Photos of Enterococcus

Podcasts & MP3s on Enterococcus

Videos on Enterococcus

Evidence Based Medicine

Cochrane Collaboration on Enterococcus

Bandolier on Enterococcus

TRIP on Enterococcus

Clinical Trials

Ongoing Trials on Enterococcus at Clinical Trials.gov

Trial results on Enterococcus

Clinical Trials on Enterococcus at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Enterococcus

NICE Guidance on Enterococcus

NHS PRODIGY Guidance

FDA on Enterococcus

CDC on Enterococcus

Books

Books on Enterococcus

News

Enterococcus in the news

Be alerted to news on Enterococcus

News trends on Enterococcus

Commentary

Blogs on Enterococcus

Definitions

Definitions of Enterococcus

Patient Resources / Community

Patient resources on Enterococcus

Discussion groups on Enterococcus

Patient Handouts on Enterococcus

Directions to Hospitals Treating Enterococcus

Risk calculators and risk factors for Enterococcus

Healthcare Provider Resources

Symptoms of Enterococcus

Causes & Risk Factors for Enterococcus

Diagnostic studies for Enterococcus

Treatment of Enterococcus

Continuing Medical Education (CME)

CME Programs on Enterococcus

International

Enterococcus en Espanol

Enterococcus en Francais

Business

Enterococcus in the Marketplace

Patents on Enterococcus

Experimental / Informatics

List of terms related to Enterococcus

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Enterococcus is a genus of lactic acid bacteria of the phylum Firmicutes. Members of this genus were classified as Group D Streptococcus until 1984 when genomic DNA analysis indicated that a separate genus classification was appropriate.[1] Important clinical infections caused by Enterococcus include urinary tract infections, bacteremia, bacterial endocarditis, diverticulitis, and meningitis.[2] Sensitive strains of these bacteria can be treated with ampicillin and vancomycin.[3] However, the most important feature of this genus is their high level of endemic antibiotic resistance.

Microbiology

Enterococcus is a genus of lactic acid bacteria of the phylum Firmicutes. Members of this genus were classified as Group D Streptococcus until 1984 when genomic DNA analysis indicated that a separate genus classification was appropriate.[4] Enterococci are Gram-positive cocci which often occur in pairs (diplococci) and are difficult to distinguish from Streptococci on physical characteristics alone. Two species are common commensal organisms in the intestines of humans: E. faecalis (90-95%) and E. faecium (5-10%). Enterococci are facultative anaerobic organisms, i.e. they prefer the use of oxygen, but they can survive in the absence of oxygen.[5] They typically exhibit gamma-hemolysis on sheep's blood agar.

Clinical Infections

Treatment

  • From a medical standpoint, the most important feature of this genus is their high level of endemic antibiotic resistance. Some Enterococci are intrinsically resistant to β-lactam-based antibiotics (some penicillins and virtually all cephalosporins) as well as many aminoglycosides.[2] In the last two decades, particularly virulent strains of Enterococcus which are resistant to vancomycin (Vancomycin-resistant enterococcus, or VRE) have emerged in nosocomial infections of hospitalized patients especially in the US. Other developed countries such as the UK have been spared this epidemic, and in 2005, Singapore managed to halt an epidemic of VRE. VRE may be treated with Quinupristin/dalfopristin (Synercid) with response rates of approximately 70%.[7]

Prevention

Water Quality

  • The acceptable level of water contamination is very low, for example in the state of Hawaii, with among the strictest tolerances in the United States, the limit for water off its beaches is 7 colony forming units per 100 ml of water, above which the state may post warnings to stay out of the ocean.[8]
  • In 2004, Enterococcus spp. took the place of fecal coliform as the new federal standard for water quality at public beaches. It is believed to provide a higher correlation than fecal coliform with many of the human pathogens often found in sewage.[9]

Gallery

References

  1. Schleifer KH; Kilpper-Balz R (1984). "Transfer of Streptococcus faecalis and Streptococcus faecium to the genus Enterococcus nom. rev. as Enterococcus faecalis comb. nov. and Enterococcus faecium comb. nov". Int. J. Sys. Bacteriol. 34: 31&ndash, 34.
  2. 2.0 2.1 2.2 Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed. ed.). McGraw Hill. pp. 294&ndash, 5. ISBN 0-8385-8529-9.
  3. 3.0 3.1 Pelletier LL Jr. (1996). Microbiology of the Circulatory System. in: Baron's Medical Microbiology (Baron S et al, eds.) (4th ed. ed.). Univ of Texas Medical Branch. ISBN 0-9631172-1-1.
  4. Schleifer KH; Kilpper-Balz R (1984). "Transfer of Streptococcus faecalis and Streptococcus faecium to the genus Enterococcus nom. rev. as Enterococcus faecalis comb. nov. and Enterococcus faecium comb. nov". Int. J. Sys. Bacteriol. 34: 31&ndash, 34.
  5. Fischetti VA; Novick RP; Ferretti JJ; Portnoy DA; Rood JI (editors) (2000). Gram-Positive Pathogens. ASM Press. ISBN 1-55581-166-3.
  6. Guardado R, Asensi V, Torres JM; et al. (2006). "Post-surgical enterococcal meningitis: clinical and epidemiological study of 20 cases". Scand. J. Infect. Dis. 38 (8): 584–8. doi:10.1080/00365540600606416. PMID 16857599.
  7. Tünger A, Aydemir S, Uluer S, Cilli F (2004). "In vitro activity of linezolid & quinupristin/dalfopristin against Gram-positive cocci". Indian J Med Res. 120 (6): 546–52. PMID 15654141.
  8. "Clean Water Branch". Hawaii State Department of Health. Retrieved 2007-02-08.
  9. Jin G, Jeng HW, Bradford H, Englande AJ (2004). "Comparison of E. coli, enterococci, and fecal coliform as indicators for brackish water quality assessment". Water Environ. Res. 76 (3): 245–55. doi:10.2175/106143004X141807. PMID 15338696.
  10. 10.0 10.1 10.2 10.3 10.4 10.5 10.6 10.7 "Public Health Image Library (PHIL)".

de:Enterokokken it:Enterococcus sr:Ентерококе sv:Enterokocker


Template:WH Template:WS