Endometriosis physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Joseph Nasr, M.D.[2], Aravind Kuchkuntla, M.B.B.S[3], Mohammed Abdelwahed M.D[4]

Overview

Examination findings on digital vaginal examination and speculum examination include a fixed retroverted uterus, palpable nodularity of the uterosacral ligaments, and cul-de-sac with narrowing of the posterior fornix. Reduced uterine mobility and posterior cul-de-sac tenderness are additional findings suggestive of deep infiltrating disease. Physical examination may be normal in some patients, and absence of findings does not exclude endometriosis.[1][2]

Physical Examination

Physical examination findings in a patient with endometriosis include:[3]

HEENT

Patient may have:

Respiratory

Abdominal examination

  • Lower abdominal tenderness
  • Fixed and tender retroverted uterus (on bi-manual examination)
  • Adnexal mass suggestive of ovarian endometrioma (if present and sufficiently large).[4]

Digital examination of the vagina

Common physical examination findings on digital examination include:[5]

Pelvic Floor Examination

  • Pelvic floor muscle tenderness may be present.[6][7]
  • Reproduction of pain with palpation of pelvic floor muscles may occur.[6][7]
  • Myofascial trigger points may be identified on examination.[6][7]

Speculum examination of the vagina

Speculum examination may reveal:

References

  1. 1.0 1.1 1.2 Pashkunova D, Darici E, Senft B, et al. Lesion size and location in deep infiltrating bowel endometriosis: correlation with gastrointestinal dysfunction and pain. Acta Obstet Gynecol Scand.2024;103(9):1764-1770. doi:10.1111/aogs.14921
  2. 2.0 2.1 2.2 Vercellini P, Fedele L, Aimi G, Pietropaolo G, Consonni D, Crosignani PG. Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: a multivariate analysis of over 1000 patients. Hum Reprod. 2007;22(1):266-271. doi:10.1093/humrep/del339
  3. Cranney R, Condous G, Reid S (2017). "An update on the diagnosis, surgical management, and fertility outcomes for women with endometrioma". Acta Obstet Gynecol Scand. 96 (6): 633–643. doi:10.1111/aogs.13114. PMID 28186620.
  4. Nisenblat V, Bossuyt PM, Farquhar C, Johnson N, Hull ML. Imaging modalities for the non-invasive diagnosis of endometriosis. Cochrane Database Syst Rev. 2016;2(2):CD009591. doi:10.1002/14651858.CD009591.pub2
  5. Vercellini P, Trespidi L, De Giorgi O, Cortesi I, Parazzini F, Crosignani PG (1996). "Endometriosis and pelvic pain: relation to disease stage and localization". Fertil Steril. 65 (2): 299–304. PMID 8566252.
  6. 6.0 6.1 6.2 Coxon L, Demetriou L, Vincent K. Current developments in endometriosis-associated pain. Cell Rep Med. 2024;5(10):101769. doi:10.1016/j.xcrm.2024.101769
  7. 7.0 7.1 7.2 Kaplan CM, Kelleher E, Irani A, Schrepf A, Clauw DJ, Harte SE. Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms. Nat Rev Neurol. 2024;20(6):347-363. doi:10.1038/s41582-024-00966-8