ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
PDB rendering based on 1d8z.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1d8z​, 1d9a​, 1fnx​, 1fxl​, 1g2e​
Identifiers
Symbols	ELAVL4 ; HUD; PNEM
External IDs	Template:OMIM5 Template:MGI HomoloGene: 40729
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D), also known as ELAVL4, is a human gene.

Further reading

• Dalmau J, Furneaux HM, Cordon-Cardo C, Posner JB (1992). "The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues". Am. J. Pathol. 141 (4): 881–6. PMID 1415481.CS1 maint: Multiple names: authors list (link)
• Szabo A, Dalmau J, Manley G; et al. (1991). "HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal". Cell. 67 (2): 325–33. PMID 1655278.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Graus F, Ferrer I (1990). "Analysis of a neuronal antigen (Hu) expression in the developing rat brain detected by autoantibodies from patients with paraneoplastic encephalomyelitis". Neurosci. Lett. 112 (1): 14–8. PMID 2166930.
• Sekido Y, Bader SA, Carbone DP; et al. (1994). "Molecular analysis of the HuD gene encoding a paraneoplastic encephalomyelitis antigen in human lung cancer cell lines". Cancer Res. 54 (18): 4988–92. PMID 8069866.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Muresu R, Baldini A, Gress T; et al. (1993). "Mapping of the gene coding for a paraneoplastic encephalomyelitis antigen (HuD) to human chromosome site 1p34". Cytogenet. Cell Genet. 65 (3): 177–8. PMID 8222755.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Torà M, Graus F, de Bolòs C, Real FX (1997). "Cell surface expression of paraneoplastic encephalomyelitis/sensory neuronopathy-associated Hu antigens in small-cell lung cancers and neuroblastomas". Neurology. 48 (3): 735–41. PMID 9065557.CS1 maint: Multiple names: authors list (link)
• Lazarova DL, Spengler BA, Biedler JL, Ross RA (1999). "HuD, a neuronal-specific RNA-binding protein, is a putative regulator of N-myc pre-mRNA processing/stability in malignant human neuroblasts". Oncogene. 18 (17): 2703–10. doi:10.1038/sj.onc.1202621. PMID 10348344.CS1 maint: Multiple names: authors list (link)
• Park S, Myszka DG, Yu M; et al. (2000). "HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA". Mol. Cell. Biol. 20 (13): 4765–72. PMID 10848602.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang X, Tanaka Hall TM (2001). "Structural basis for recognition of AU-rich element RNA by the HuD protein". Nat. Struct. Biol. 8 (2): 141–5. doi:10.1038/84131. PMID 11175903.
• Beckel-Mitchener AC, Miera A, Keller R, Perrone-Bizzozero NI (2002). "Poly(A) tail length-dependent stabilization of GAP-43 mRNA by the RNA-binding protein HuD". J. Biol. Chem. 277 (31): 27996–8002. doi:10.1074/jbc.M201982200. PMID 12034726.CS1 maint: Multiple names: authors list (link)
• Behrends U, Jandl T, Golbeck A; et al. (2002). "Novel products of the HUD, HUC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library". Int. J. Cancer. 100 (6): 669–77. doi:10.1002/ijc.10550. PMID 12209604.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Aronov S, Aranda G, Behar L, Ginzburg I (2003). "Visualization of translated tau protein in the axons of neuronal P19 cells and characterization of tau RNP granules". J. Cell. Sci. 115 (Pt 19): 3817–27. PMID 12235292.CS1 maint: Multiple names: authors list (link)
• Angenstein F, Evans AM, Settlage RE; et al. (2002). "A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons". J. Neurosci. 22 (20): 8827–37. PMID 12388589.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Deschenes-Furry J, Belanger G, Perrone-Bizzozero N, Jasmin BJ (2003). "Post-transcriptional regulation of acetylcholinesterase mRNAs in nerve growth factor-treated PC12 cells by the RNA-binding protein HuD". J. Biol. Chem. 278 (8): 5710–7. doi:10.1074/jbc.M209383200. PMID 12468554.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Plonquet A, Garcia-Pons F, Fernandez E; et al. (2004). "Peptides derived from the onconeural HuD protein can elicit cytotoxic responses in HHD mouse and human". J. Neuroimmunol. 142 (1–2): 93–100. PMID 14512168.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Saito K, Fujiwara T, Katahira J; et al. (2004). "TAP/NXF1, the primary mRNA export receptor, specifically interacts with a neuronal RNA-binding protein HuD". Biochem. Biophys. Res. Commun. 321 (2): 291–7. doi:10.1016/j.bbrc.2004.06.140. PMID 15358174.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rousseau A, Benyahia B, Dalmau J; et al. (2005). "T cell response to Hu-D peptides in patients with anti-Hu syndrome". J. Neurooncol. 71 (3): 231–6. doi:10.1007/s11060-004-1723-1. PMID 15735910.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Noureddine MA, Qin XJ, Oliveira SA; et al. (2005). "Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease". Hum. Genet. 117 (1): 27–33. doi:10.1007/s00439-005-1259-2. PMID 15827745.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)