Dienestrol

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Dienestrol
Dienestrol.svg
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code
Pharmacokinetic data
Protein binding50 to 80%
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
E number{{#property:P628}}
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Chemical and physical data
FormulaC18H18O2
Molar mass266.334 g/mol
3D model (JSmol)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Dienestrol is a synthetic estrogen.

Synthesis

Dienestrol synthesis:[1]
  1. Pinacol coupling of p-acetoxy-propiophenone.
  2. Dehydration of the thus-obtained glycol with a mixture of acetyl chloride and acetic anhydride leads to the transoid diene system (bis-β-Methylstyrene-type).
  3. Saponification removes the acetate groups and thus affords dienestrol.

See also

References


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