Diabetic nephropathy epidemiology and demographics
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In the United States, prevalence of diabetic nephropathy (DN) has increased from 7.4% to 9.6% within a 20 years period (1988 to 2008), and this trend will likely continue due to the increasing incidence of diabetes in the American populace . Studies by de Boer et al showed that DN accounts for 44% of new ESRD cases with 6% attributed to type 1 DM, 38% attributed to type 2 DM, and a projected increase of 3 million cases over the course of 20 years. This increased incidence and prevalence of DN is notably greater among African Americans, Asians, and Native Americans than it is among Caucasians.
Epidemiology and Demographics
- It is estimated that half of the diabetic patients will develop diabetic nephropathy after 20 years of the onset of the disease.
- Diabetic nephropathy is the most common etiology of nephropathy and dialysis in the Western world.
- The worldwide burden of diabetic nephropathy seems to be on the rise, with an incidence rising by 150% per one decade in USA, Europe, and Japan and a prevalence increasing from 6.4% in 2010 and estimated to reach 7.7% in 2030.
- Costs due to diabetic nephropathy reach as high as 30-40 billion USD annually in the USA only.
- The burden of diabetic nephropathy from type II diabetes is far more significant than that of type I diabetes.
- Advanced age in type 2 diabetes and early diagnosis in type 1 diabetes are associated with higher risk of DN.
- Diabetic nephropathy has no sex predilection.
- Most of the cases of diabetic nephropathy develop after 10 years of the diagnosis with most of the cases are diagnosed between 10 and 20 years after the onset of the disease.
- Diabetic nephropathy tends to occur in elderly patients with type 2 DM who have the disease for a long period of time.
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