DA-R-EPOCH regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:DA-EPOCH-R; Dose-adjusted Etoposide/Vincristine/Doxorubicin/Cyclophosphamide/Prednisone/Rituximab Regimen; EPOCH-R regimen; EPOCH-R; EPOCH-R regimen; Etoposide-Prednisone-Oncovin-Cyclophosphamide-Hydroxydaunorubicin-Rituximab Regimen

Overview

DA-R-EPOCH regimen refers to a chemotherapy regimen consisting of Dose-adjusted etoposide, prednisone, vincristine (Oncovin) ,Cyclophosphamide and doxorubicin (hydroxydaunorubicin hycrochloride), which may be used in combination with rituximab (R-EPOCH) for the treatment of various aggressive B cell and T cell non-Hodgkin lymphomas and HIV-associated B-cell non-Hodgkin lymphoma

Regimen

DADose-adjusted

RRituximab

EEtoposide

PPrednisone

Ovincristine (Oncovin)

CCyclophosphamide

Hdoxorubicin (Hydroxydaunorubicin hycrochloride)

Indications

• Primary mediastinal(thymic)B-cell lymphoma