D-lactate dehydrogenase (cytochrome c-553)

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In enzymology, a D-lactate dehydrogenase (cytochrome c-553) (EC is an enzyme that catalyzes the chemical reaction

(R)-lactate + 2 ferricytochrome c-553 pyruvate + 2 ferrocytochrome c-553

Thus, the two substrates of this enzyme are (R)-lactate and ferricytochrome c-553, whereas its two products are pyruvate and ferrocytochrome c-553.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is (R)-lactate:ferricytochrome-c-553 2-oxidoreductase. This enzyme participates in pyruvate metabolism.


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  • Ogata M, Arihara K and Yagi T (Tokyo). "D-Lactate dehydrogenase of Desulfovibrio vulgaris". J. Biochem.: 1423&ndash, 1431. Check date values in: |date= (help)

External links

The CAS registry number for this enzyme class is 37250-79-6.

Gene Ontology (GO) codes