Cytopathic effect

Jump to: navigation, search

WikiDoc Resources for Cytopathic effect

Articles

Most recent articles on Cytopathic effect

Most cited articles on Cytopathic effect

Review articles on Cytopathic effect

Articles on Cytopathic effect in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Cytopathic effect

Images of Cytopathic effect

Photos of Cytopathic effect

Podcasts & MP3s on Cytopathic effect

Videos on Cytopathic effect

Evidence Based Medicine

Cochrane Collaboration on Cytopathic effect

Bandolier on Cytopathic effect

TRIP on Cytopathic effect

Clinical Trials

Ongoing Trials on Cytopathic effect at Clinical Trials.gov

Trial results on Cytopathic effect

Clinical Trials on Cytopathic effect at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Cytopathic effect

NICE Guidance on Cytopathic effect

NHS PRODIGY Guidance

FDA on Cytopathic effect

CDC on Cytopathic effect

Books

Books on Cytopathic effect

News

Cytopathic effect in the news

Be alerted to news on Cytopathic effect

News trends on Cytopathic effect

Commentary

Blogs on Cytopathic effect

Definitions

Definitions of Cytopathic effect

Patient Resources / Community

Patient resources on Cytopathic effect

Discussion groups on Cytopathic effect

Patient Handouts on Cytopathic effect

Directions to Hospitals Treating Cytopathic effect

Risk calculators and risk factors for Cytopathic effect

Healthcare Provider Resources

Symptoms of Cytopathic effect

Causes & Risk Factors for Cytopathic effect

Diagnostic studies for Cytopathic effect

Treatment of Cytopathic effect

Continuing Medical Education (CME)

CME Programs on Cytopathic effect

International

Cytopathic effect en Espanol

Cytopathic effect en Francais

Business

Cytopathic effect in the Marketplace

Patents on Cytopathic effect

Experimental / Informatics

List of terms related to Cytopathic effect

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cytopathic effect or cytopathogenic effect (abbreviated CPE) refers to damage to host cells during virus invasion. This damage is measurable by obtaining viral titers. Degenerative changes in cells can also be studied in tissue culture.

When in tissue culture the spread of virus is restricted by an overlay of agar or other suitable substance. This barrier means the cytopathic effect may lead to the formation of a viral plaque.[1] Thus identification of a viral infection can be made by examining the characteristic cytopathic effect produced on different cell sheets. This method however is relatively slow and not all viruses will grow on cell sheets. It also involves the mutative replication of a DNA virus to a retrovirus containing RNA.

Cytopathic effects have been shown in conjunction with non-viral infections as well, such as those changes seen in fibroblasts during the early lesion of periodontal disease.[2]

Not all viruses cause a measurable cytopathic effect. These include two human coronaviruses HCoV-229E and HCoV-OC43. [3]

See Also

References

  1. Medical Microbiology, Mims and Playfair, Mosby: Europe, 1993, 18.8.
  2. Page, RC; Schroeder, HE. "Pathogenesis of Inflammatory Periodontal Disease: A Summary of Current Work." Lab Invest 1976;34(3):235-249
  3. Francine Lambert, Hélène Jacomy1 Gabriel Marceau1, Pierre J Talbot*1 Titration of Human Coronaviruses, HCoV-229E and HCoV-OC43, by an Indirect Immunoperoxidase Assay. SARS- and Other Coronaviruses : Laboratory Protocols. Series: Methods in Molecular Biology. Volume: 454. Pub. Date: May-01-2008. 93-102. DOI: 10.1007/978-1-59745-181-9_8

Linked-in.jpg