Cyclic vomiting syndrome medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
There is no set cure for Cyclic Vomiting Syndrome, but there are medications that can be used to treat, intervene in, and prevent attacks. There is a growing body of publications on either individual cases or experiences of cohorts of CVS patients. Treatment is usually on an individual basis, based on trial and error.
The most common therapeutic strategies for those already in an attack are maintenance of salt balance by appropriate intravenous fluids and; in some cases, sedation. Having vomited for a long period prior to attending a hospital, patients are typically severely dehydrated and suffer from massive volume depletion. Abortive therapy has limited success, but for a number of patients potent anti-emetic drugs such as ondansetron (Zofran) or granisetron (Kytril), dronabinol (Marinol), and more recently (and under careful medical supervision) aprepitant (Emend) may be helpful in either preventing an attack, aborting an attack or reducing the severity of an attack.
Treatments have been reviewed[1].
Meloxicam daily may prevent episodes[2]
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References
- ↑ Fleisher DR, Gornowicz B, Adams K, Burch R, Feldman EJ (2005). "Cyclic Vomiting Syndrome in 41 adults: the illness, the patients, and problems of management". BMC Med. 3: 20. doi:10.1186/1741-7015-3-20. PMC 1326207. PMID 16368014.
- ↑ Vidula MK, Wadhwani A, Roberts K, Berkowitz LL (2014). "Use of a once-daily NSAID in treatment of cyclic vomiting syndrome". J Gen Intern Med. 29 (3): 543–6. doi:10.1007/s11606-013-2624-9. PMC 3930795. PMID 24129856.