CyBorD regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:Bortezomib/Cyclophosphamide/Dexamethasone Regimen; CyBorD; VCD; Velcade-Cyclophosphamide-Dexamethasone

Overview

CyBorD regimen refers to a treatment regimen consisting of a combination of cyclophosphamide, bortezomib (Velcade) and dexamethasone three-drug induction regimen for untreated transplant-eligible multiple myeloma patients^[1] and AL amyloidosis^[2]

Regimen

CyCyclophosphamide

BorBortezomib (Velcade)

DDexamethasone

Indications

Multiple myeloma^[1]

AL amyloidosis^[2]

References

↑ ^1.0 ^1.1 Areethamsirikul N, Masih-Khan E, Chu CM, Jimenez-Zepeda V, Reece DE, Trudel S; et al. (2015). "CyBorD induction therapy in clinical practice". Bone Marrow Transplant. 50 (3): 375–9. doi:10.1038/bmt.2014.288. PMID 25599165.
↑ ^2.0 ^2.1 Mikhael JR, Schuster SR, Jimenez-Zepeda VH, Bello N, Spong J, Reeder CB; et al. (2012). "Cyclophosphamide-bortezomib-dexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis". Blood. 119 (19): 4391–4. doi:10.1182/blood-2011-11-390930. PMC 3557400. PMID 22331188.

[pmid25599165-1] 1.0 ^1.1 Areethamsirikul N, Masih-Khan E, Chu CM, Jimenez-Zepeda V, Reece DE, Trudel S; et al. (2015). "CyBorD induction therapy in clinical practice". Bone Marrow Transplant. 50 (3): 375–9. doi:10.1038/bmt.2014.288. PMID 25599165.

[pmid22331188-2] 2.0 ^2.1 Mikhael JR, Schuster SR, Jimenez-Zepeda VH, Bello N, Spong J, Reeder CB; et al. (2012). "Cyclophosphamide-bortezomib-dexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis". Blood. 119 (19): 4391–4. doi:10.1182/blood-2011-11-390930. PMC 3557400. PMID 22331188.

[1]

[2]

CyBorD regimen

Overview

Regimen

Indications

References

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