Congestive heart failure iron

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];

Overview

Iron

Indications for Iron

Background

European Society of Cardiology's 2021 HF guidelines

The ECS states[1]:

  • "It is recommended that all patients with HF be periodically screened for anaemia and iron deficiency with a full blood count, serum ferritin concentration, and TSAT." a Class of recommendation: I "Is recommended or is indicated"; Level of evidence C "Consensus of opinion of the experts and/or small studies, retrospective studies, registries"
  • "Intravenous iron supplementation with ferric carboxymaltose should be considered in symptomatic patients with LVEF <45% and iron deficiency, defined as serum ferritin <100 ng/mL or serum ferritin 100299 ng/mL with TSAT <20%, to alleviate HF symptoms, improve exercise capacity and QOL"
  • "Intravenous iron supplementation with ferric carboxymaltose should be considered in symptomatic HF patients recently hospitalized for HF and with LVEF <50% and iron deficiency, defined as serum ferritin <100 ng/mL or serum ferritin 100299 ng/mL with TSAT <20%, to reduce the risk of HF hospitalization"

Trials

References

  1. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M; et al. (2021). "2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure". Eur Heart J. 42 (36): 3599–3726. doi:10.1093/eurheartj/ehab368. PMID 34447992 Check |pmid= value (help).

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