Chordoma pathophysiology

Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.

Chordoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Pathophysiology
Epidemiology and Demographics
Risk Factors
Screening
Causes
Differentiating Chordoma from other Diseases
Natural History, Complications and Prognosis
Diagnosis
Staging
History and Symptoms
Physical Examination
Laboratory Findings
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Chordoma pathophysiology On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Chordoma pathophysiology All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Chordoma pathophysiology
CDC on Chordoma pathophysiology
Chordoma pathophysiology in the news
Blogs on Chordoma pathophysiology
Directions to Hospitals Treating Chordoma
Risk calculators and risk factors for Chordoma pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

There are three histological variants of chordoma: classical, chondroid and dedifferentiated. The histological appearance of classical chordoma is of a lobulated tumor composed of groups of cells separated by fibrous septa. The cells have small round nuclei and abundant vacuolated cytoplasm, sometimes described as physaliferous (resembling a spider's web). Chondroid chordomas histologically show features of both chordoma and chondrosarcoma.

References

Template:WikiDoc Sources