Cardiac troponin I (cTnI) and T (cTnT)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Cardiac troponin I (cTnI) and T (cTnT) are the current gold standards for detecting myocardial necrosis. Elevation in the setting of NSTE ACS is associated with a markedly increased risk of death and reinfarction. GP IIb/IIIa inhibitors can blunt the magnitude of this troponin release in NSTE ACS. Furthermore, troponin elevation identifies a subset of patients who enjoy the greatest benefit from both GP IIb/IIIa inhibition and early invasive therapy. [1] [2]

References

  1. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X


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