COX1

Cytochrome c oxidase subunit I
File:PBB Protein COX1 image.jpg PDB rendering based on 1occ.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1occ​, 1oco​, 1ocr​, 1ocz​, 1v54​, 1v55​, 2dyr​, 2dys​, 2eij​, 2eik​, 2eil​, 2eim​, 2ein​, 2occ​
Identifiers
Symbols	COX1 ; MTCO1
External IDs	Template:MGI HomoloGene: 5016
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Cytochrome c oxidase subunit I, also known as COX1, is a human protein and gene. It belongs to cytochrome c oxidase subunit I protein family.

Further reading

• Torroni A, Achilli A, Macaulay V; et al. (2006). "Harvesting the fruit of the human mtDNA tree". Trends Genet. 22 (6): 339–45. doi:10.1016/j.tig.2006.04.001. PMID 16678300.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bodenteich A, Mitchell LG, Polymeropoulos MH, Merril CR (1993). "Dinucleotide repeat in the human mitochondrial D-loop". Hum. Mol. Genet. 1 (2): 140. PMID 1301157.CS1 maint: Multiple names: authors list (link)
• Brown MD, Yang CC, Trounce I; et al. (1992). "A mitochondrial DNA variant, identified in Leber hereditary optic neuropathy patients, which extends the amino acid sequence of cytochrome c oxidase subunit I.". Am. J. Hum. Genet. 51 (2): 378–85. PMID 1322638.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lu X, Walker T, MacManus JP, Seligy VL (1992). "Differentiation of HT-29 human colonic adenocarcinoma cells correlates with increased expression of mitochondrial RNA: effects of trehalose on cell growth and maturation". Cancer Res. 52 (13): 3718–25. PMID 1377597.CS1 maint: Multiple names: authors list (link)
• Marzuki S, Noer AS, Lertrit P; et al. (1992). "Normal variants of human mitochondrial DNA and translation products: the building of a reference data base". Hum. Genet. 88 (2): 139–45. PMID 1757091.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Moraes CT, Andreetta F, Bonilla E; et al. (1991). "Replication-competent human mitochondrial DNA lacking the heavy-strand promoter region". Mol. Cell. Biol. 11 (3): 1631–7. PMID 1996112.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Attardi G, Chomyn A, Doolittle RF; et al. (1987). "Seven unidentified reading frames of human mitochondrial DNA encode subunits of the respiratory chain NADH dehydrogenase". Cold Spring Harb. Symp. Quant. Biol. 51 Pt 1: 103–14. PMID 3472707.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chomyn A, Cleeter MW, Ragan CI; et al. (1986). "URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit". Science. 234 (4776): 614–8. PMID 3764430.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chomyn A, Mariottini P, Cleeter MW; et al. (1985). "Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase". Nature. 314 (6012): 592–7. PMID 3921850.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sanger F, Coulson AR, Barrell BG; et al. (1981). "Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing". J. Mol. Biol. 143 (2): 161–78. PMID 6260957.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Montoya J, Ojala D, Attardi G (1981). "Distinctive features of the 5'-terminal sequences of the human mitochondrial mRNAs". Nature. 290 (5806): 465–70. PMID 7219535.CS1 maint: Multiple names: authors list (link)
• Horai S, Hayasaka K, Kondo R; et al. (1995). "Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs". Proc. Natl. Acad. Sci. U.S.A. 92 (2): 532–6. PMID 7530363.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gattermann N, Retzlaff S, Wang YL; et al. (1997). "Heteroplasmic point mutations of mitochondrial DNA affecting subunit I of cytochrome c oxidase in two patients with acquired idiopathic sideroblastic anemia". Blood. 90 (12): 4961–72. PMID 9389715.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bröker S, Meunier B, Rich P; et al. (1998). "MtDNA mutations associated with sideroblastic anaemia cause a defect of mitochondrial cytochrome c oxidase". Eur. J. Biochem. 258 (1): 132–8. PMID 9851701.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Andrews RM, Kubacka I, Chinnery PF; et al. (1999). "Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA". Nat. Genet. 23 (2): 147. doi:10.1038/13779. PMID 10508508.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Karadimas CL, Greenstein P, Sue CM; et al. (2000). "Recurrent myoglobinuria due to a nonsense mutation in the COX I gene of mitochondrial DNA". Neurology. 55 (5): 644–9. PMID 10980727.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ingman M, Kaessmann H, Pääbo S, Gyllensten U (2001). "Mitochondrial genome variation and the origin of modern humans". Nature. 408 (6813): 708–13. doi:10.1038/35047064. PMID 11130070.CS1 maint: Multiple names: authors list (link)
• Finnilä S, Lehtonen MS, Majamaa K (2001). "Phylogenetic network for European mtDNA". Am. J. Hum. Genet. 68 (6): 1475–84. PMID 11349229.CS1 maint: Multiple names: authors list (link)
• Maca-Meyer N, González AM, Larruga JM; et al. (2003). "Major genomic mitochondrial lineages delineate early human expansions". BMC Genet. 2: 13. PMID 11553319.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)