CMF regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:CMF; CMF Regimen; CMF regimen; CTX/5-FU/MTX; Cyclophosphamide/Fluorouracil/Methotrexate; Cytoxan-Methotrexate-Fluorouracil Regimen

Overview

CMF regimen refers to a chemotherapy regimen consisting of cyclophosphamide, methotrexate, and fluorouracil, which may be used in the adjuvant setting for the treatment of nonmetastatic breast cancer or alone for the treatment of metastatic breast cancer.

Regimen

CCyclophosphamide

MMethotrexate

FFluorouracil

Indications

• Nonmetastatic breast cancer
• Metastatic breast cancer.