CIRH1A

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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Cirhin is a protein that in humans is encoded by the CIRH1A gene.[1][2][3] It has been associated with North American Indian childhood cirrhosis (not to be confused with Indian Childhood Cirrhosis which has greatly decreased over the past 100 years and was thought to be secondary to the use of various herbal remedies), a form of cirrhosis of the liver occurring in American Indian children from the Abitibi region of northern Quebec.[4]


References

  1. Betard C, Rasquin-Weber A, Brewer C, Drouin E, Clark S, Verner A, Darmond-Zwaig C, Fortin J, Mercier J, Chagnon P, Fujiwara TM, Morgan K, Richter A, Hudson TJ, Mitchell GA (Aug 2000). "Localization of a recessive gene for North American Indian childhood cirrhosis to chromosome region 16q22-and identification of a shared haplotype". Am J Hum Genet. 67 (1): 222–8. doi:10.1086/302993. PMC 1287080. PMID 10820129.
  2. Chagnon P, Michaud J, Mitchell G, Mercier J, Marion JF, Drouin E, Rasquin-Weber A, Hudson TJ, Richter A (Nov 2002). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis". Am J Hum Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.
  3. "Entrez Gene: CIRH1A cirrhosis, autosomal recessive 1A (cirhin)".
  4. Chagnon P, Michaud J, Mitchell G, et al. (2002). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis". Am. J. Hum. Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.

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Further reading