CD1d

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CD1d molecule
Identifiers
SymbolCD1D
Alt. symbolsCD1
Entrez912
HUGO1637
OMIM188410
RefSeqNM_001766
UniProtP15813
Other data
LocusChr. 1 q22-q23

CD1d is a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. It is the only member of the group 2 CD1 molecules.

CD1d presented lipid antigens activate a special class of T cells, known as Natural Killer T (NKT) cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and IL-4 production.

Nomenclature

  • CD1d is also known as R3G1

External links

ca:CD1d



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