Burkholderia mallei

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Burkholderia mallei
Scientific classification
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Beta Proteobacteria
Order: Burkholderiales
Family: Burkholderiaceae
Genus: Burkholderia
Species: B. mallei
Binomial name
Burkholderia mallei
(Zopf 1885)
Yabuuchi et al. 1993

Bacillus mallei Zopf 1885
Pfeifferella mallei (Zopf 1885) Buchanan 1918
Malleomyces mallei (Zopf 1885) Pribram 1933
Actinobacillus mallei (Zopf 1885) Thompson 1933
Loefferella mallei (Zopf 1885) Holden 1935
Acinetobacter mallei (Zopf 1885) Steel and Cowan 1964
Pseudomonas mallei (Zopf 1885) Redfearn et al. 1966

Burkholderia mallei is a gram-negative bipolar aerobic bacterium, a Burkholderia-genus human and animal pathogen causing Glanders; the Latin name of this disease (malleus) gave name to the causative agent species. Unlike closely related Burkholderia pseudomallei and other genus members, the bacterium is nonmotile; its shape is something in between a rod and a coccus measuring some 1.5–3 μm in length and 0.5–1μm in diameter with rounded ends.

The bacterium is susceptible to numerous disinfectants including benzalkonium chloride, iodine, mercuric chloride, potassium permanganate, 1% sodium hypochlorite and ethanol. The microorganism can also be destroyed by heating or UV. Antibiotics such as streptomycin, amikacin, tetracycline, doxycycline and sulfathiazole have been reported to be effective against the bacteria in vitro.

B. mallei as well as B. pseudomallei have a history of being on a list of potential biological warfare agents.

this bacteria is one of the first to be identified containing a type VI secretion system which is important for its patogenesity [1]

External Links

[1] Mark A. Schell, Ricky L, Ulrich et al. Type VI secretion is a major virulence determinant in ?Burkholderia Mallei. Molecular Microbiology (2007) 64(6) pp1466-1485 Template:Proteobacteria-stub

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