Bruton disease

Bruton disease

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Bruton disease or Bruton agammaglobulinemia is a hereditary type of agammaglobulinemia that is a sex-linked recessive disorder characterized by a deficiency of all types of immunoglobulins, reflecting a failure of the entire humoral antibody marrow system; the thymus may be normal, but the lymph nodes and spleen lack lymph cell follicles.

Differential diagnosis

• Acrodermatitis enteropathica
• Ataxia telangiectasia
• Atopic dermatitis
• Avitaminosis A
• Common Variable Immunodeficiency
• Severe Combined Immunodeficiency

[[Category:Immunology]

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