BCAN

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Brevican
Identifiers
Symbols BCAN ; BEHAB; CSPG7; MGC13038
External IDs Template:OMIM5 Template:MGI HomoloGene7244
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Brevican, also known as BCAN, is a human gene.[1]


References

  1. "Entrez Gene: BCAN brevican".

Further reading

  • Seidenbecher CI, Richter K, Rauch U; et al. (1995). "Brevican, a chondroitin sulfate proteoglycan of rat brain, occurs as secreted and cell surface glycosylphosphatidylinositol-anchored isoforms". J. Biol. Chem. 270 (45): 27206–12. PMID 7592978.
  • Aspberg A, Miura R, Bourdoulous S; et al. (1997). "The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety". Proc. Natl. Acad. Sci. U.S.A. 94 (19): 10116–21. PMID 9294172.
  • Nakamura H, Fujii Y, Inoki I; et al. (2001). "Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites". J. Biol. Chem. 275 (49): 38885–90. doi:10.1074/jbc.M003875200. PMID 10986281.
  • Olin AI, Mörgelin M, Sasaki T; et al. (2001). "The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding". J. Biol. Chem. 276 (2): 1253–61. doi:10.1074/jbc.M006783200. PMID 11038354.
  • Gary SC, Zerillo CA, Chiang VL; et al. (2001). "cDNA cloning, chromosomal localization, and expression analysis of human BEHAB/brevican, a brain specific proteoglycan regulated during cortical development and in glioma". Gene. 256 (1–2): 139–47. PMID 11054543.
  • Nomoto H, Oohashi T, Hirakawa S; et al. (2002). "Human BRAL1 and BCAN genes that belong to the link-module superfamily are tandemly arranged on chromosome 1q21-23". Acta Med. Okayama. 56 (1): 25–9. PMID 11873941.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
  • Xu XM, Chen Y, Chen J; et al. (2003). "A peptide with three hyaluronan binding motifs inhibits tumor growth and induces apoptosis". Cancer Res. 63 (18): 5685–90. PMID 14522884.
  • Bekku Y, Su WD, Hirakawa S; et al. (2004). "Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets". Mol. Cell. Neurosci. 24 (1): 148–59. PMID 14550776.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Dong Y, Han X, Xue Y; et al. (2004). "Secreted brevican mRNA is expressed in the adult rat pituitary". Biochem. Biophys. Res. Commun. 314 (3): 745–8. PMID 14741698.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Viapiano MS, Bi WL, Piepmeier J; et al. (2005). "Novel tumor-specific isoforms of BEHAB/brevican identified in human malignant gliomas". Cancer Res. 65 (15): 6726–33. doi:10.1158/0008-5472.CAN-05-0585. PMID 16061654.
  • Nakada M, Miyamori H, Kita D; et al. (2007). "Human glioblastomas overexpress ADAMTS-5 that degrades brevican". Acta Neuropathol. 110 (3): 239–46. doi:10.1007/s00401-005-1032-6. PMID 16133547.
  • Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

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