Attractin

Jump to: navigation, search
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Attractin is a protein that in humans is encoded by the ATRN gene.[1][2][3]

Attractin is a Group XI C-type lectin.

Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other isoform is a secreted protein involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines.[3]

References

  1. Duke-Cohan JS, Gu J, McLaughlin DF, Xu Y, Freeman GJ, Schlossman SF (Oct 1998). "Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions". Proc Natl Acad Sci U S A. 95 (19): 11336–41. doi:10.1073/pnas.95.19.11336. PMC 21643. PMID 9736737.
  2. Duke-Cohan JS, Morimoto C, Rocker JA, Schlossman SF (Apr 1996). "Serum high molecular weight dipeptidyl peptidase IV (CD26) is similar to a novel antigen DPPT-L released from activated T cells". J Immunol. 156 (5): 1714–21. PMID 8596018.
  3. 3.0 3.1 "Entrez Gene: ATRN attractin".

External links

Further reading




Linked-in.jpg