Adenocarcinoma of the lung medical therapy stage I
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Adenocarcinoma of the Lung Microchapters |
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Differentiating Adenocarcinoma of the Lung from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Stage I
- Shown below is the algorithm on the treatment of the stage I non-small cell lung cancer based on the 2014 NCCN Non-Small Cell Lung Cancer guidelines.[1]
| In the tumor central or peripheral? | |||||||||||||||||||||||||||||||||||||||||||
| Peripheral | Central | ||||||||||||||||||||||||||||||||||||||||||
| Is the tumor T1 or T2a? | |||||||||||||||||||||||||||||||||||||||||||
| T1ab, N0 | T2a, N0 | T1ab-2a, N0 | |||||||||||||||||||||||||||||||||||||||||
Perform a pretreatment evaluation
| Perform a pretreatment evaluation | ||||||||||||||||||||||||||||||||||||||||||
| Does the pathological evaluation showed positive disease in the mediastinal lymph nodes? | Does the pathological evaluation showed positive disease in the mediastinal lymph nodes? | ||||||||||||||||||||||||||||||||||||||||||
| Yes | No | Yes | No | ||||||||||||||||||||||||||||||||||||||||
| Click here for the stage III treatment | Is the tumor operable? | Click here for the stage III treatment | Is the tumor operable? | ||||||||||||||||||||||||||||||||||||||||
| Yes | No | Yes | No | ||||||||||||||||||||||||||||||||||||||||
| Surgical resection + lymph node dissection | stereotactic ablative radiation therapy | Surgical resection + lymph node dissection | Does the patient presents metastasis to ipsilateral peribronchial and/or hilar nodesand intrapulmonary nodes (N1)? | ||||||||||||||||||||||||||||||||||||||||
| Yes | No | ||||||||||||||||||||||||||||||||||||||||||
| chemotherapy + radiation therapy | stereotactic ablative radiation therapy Adjuvant chemotherapy should be added for high-risk stages | ||||||||||||||||||||||||||||||||||||||||||
References
- ↑ Lung cancer. National Comprehensive Cancer Network 2015. http://www.nccn.org/professionals/default.aspx