Abr, rhogef and gtpase activating protein
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| Species | Human | Mouse | |||||
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ABR, RhoGEF and GTPase activating protein is a protein that in humans is encoded by the ABR gene. [1]
Function
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Feb 2012].
References
- ↑ "Entrez Gene: ABR, RhoGEF and GTPase activating protein". Retrieved 2018-05-23.
Further reading
- Kaartinen V, Nagy A, Gonzalez-Gomez I, Groffen J, Heisterkamp N (April 2002). "Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs". Dev. Dyn. 223 (4): 517–25. doi:10.1002/dvdy.10071. PMID 11921339.
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Template:Gene-CHR HSCHR17 3 CTG2-stub
This article incorporates text from the United States National Library of Medicine, which is in the public domain.