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Alpha-1-microglobulin/bikunin precursor
PBB Protein AMBP image.jpg
PDB rendering based on 1bik.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
External IDs Template:OMIM5 Template:MGI HomoloGene1234
RNA expression pattern
PBB GE AMBP 205477 s at tn.png
More reference expression data
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Alpha-1-microglobulin/bikunin precursor, also known as AMBP, is a human gene.[1]


  1. "Entrez Gene: AMBP alpha-1-microglobulin/bikunin precursor".

Further reading

  • Akerström B, Lögdberg L, Berggård T; et al. (2000). "alpha(1)-Microglobulin: a yellow-brown lipocalin". Biochim. Biophys. Acta. 1482 (1–2): 172–84. PMID 11058759.
  • Kobayashi H, Suzuki M, Hirashima Y, Terao T (2004). "The protease inhibitor bikunin, a novel anti-metastatic agent". Biol. Chem. 384 (5): 749–54. PMID 12817471.
  • Ekström B, Berggård I (1977). "Human alpha1-microglobulin. Purification procedure, chemical and physiochemical properties". J. Biol. Chem. 252 (22): 8048–57. PMID 72071.
  • Salier JP, Simon D, Rouet P; et al. (1992). "Homologous chromosomal locations of the four genes for inter-alpha-inhibitor and pre-alpha-inhibitor family in human and mouse: assignment of the ancestral gene for the lipocalin superfamily". Genomics. 14 (1): 83–8. PMID 1385302.
  • Escribano J, Lopex-Otin C, Hjerpe A; et al. (1990). "Location and characterization of the three carbohydrate prosthetic groups of human protein HC". FEBS Lett. 266 (1–2): 167–70. PMID 1694784.
  • Diarra-Mehrpour M, Bourguignon J, Sesboüé R; et al. (1990). "Structural analysis of the human inter-alpha-trypsin inhibitor light-chain gene". Eur. J. Biochem. 191 (1): 131–9. PMID 1696200.
  • Gebhard W, Schreitmüller T, Vetr H; et al. (1990). "Complementary DNA and deduced amino acid sequences of procine alpha 1-microglobulin and bikunin". FEBS Lett. 269 (1): 32–6. PMID 1696914.
  • Falkenberg C, Grubb A, Akerström B (1990). "Isolation of rat serum alpha 1-microglobulin. Identification of a complex with alpha 1-inhibitor-3, a rat alpha 2-macroglobulin homologue". J. Biol. Chem. 265 (27): 16150–7. PMID 1697852.
  • Nazimova SV, Akulenko IV, Zaĭtseva IV; et al. (1990). "[Immunoenzyme analysis of placenta-specific alpha(1)-microglobulin in the blood serum in normal and pathological pregnancy]". Akusherstvo i ginekologiia (7): 70–2. PMID 1700638.
  • Vetr H, Gebhard W (1991). "Structure of the human alpha 1-microglobulin-bikunin gene". Biol. Chem. Hoppe-Seyler. 371 (12): 1185–96. PMID 1708673.
  • Escribano J, Grubb A, Calero M, Méndez E (1991). "The protein HC chromophore is linked to the cysteine residue at position 34 of the polypeptide chain by a reduction-resistant bond and causes the charge heterogeneity of protein HC". J. Biol. Chem. 266 (24): 15758–63. PMID 1714898.
  • Enghild JJ, Salvesen G, Hefta SA; et al. (1991). "Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor". J. Biol. Chem. 266 (2): 747–51. PMID 1898736.
  • Reisinger P, Hochstrasser K, Albrecht GJ; et al. (1985). "Human inter-alpha-trypsin inhibitor: localization of the Kunitz-type domains in the N-terminal part of the molecule and their release by a trypsin-like proteinase". Biol. Chem. Hoppe-Seyler. 366 (5): 479–83. PMID 2408638.
  • Bourguignon J, Diarra-Mehrpour M, Sesboüé R; et al. (1985). "Human inter-alpha-trypsin-inhibitor: characterization and partial nucleotide sequencing of a light chain-encoding cDNA". Biochem. Biophys. Res. Commun. 131 (3): 1146–53. PMID 2413856.
  • Méndez E, Fernández-Luna JL, Grubb A, Leyva-Cobián F (1986). "Human protein HC and its IgA complex are inhibitors of neutrophil chemotaxis". Proc. Natl. Acad. Sci. U.S.A. 83 (5): 1472–5. PMID 2419908.
  • Traboni C, Cortese R (1986). "Sequence of a full length cDNA coding for human protein HC (alpha 1 microglobulin)". Nucleic Acids Res. 14 (15): 6340. PMID 2428011.
  • Kaumeyer JF, Polazzi JO, Kotick MP (1986). "The mRNA for a proteinase inhibitor related to the HI-30 domain of inter-alpha-trypsin inhibitor also encodes alpha-1-microglobulin (protein HC)". Nucleic Acids Res. 14 (20): 7839–50. PMID 2430261.
  • Zaraĭskiĭ EI, Nazimova SV, Olefirenko GA; et al. (1990). "[Immunoenzyme analysis of placenta-specific alpha 1-microglobulin in the serum of blood donors]". Vopr. Med. Khim. 35 (5): 130–2. PMID 2482577.
  • Schreitmüller T, Hochstrasser K, Reisinger PW; et al. (1987). "cDNA cloning of human inter-alpha-trypsin inhibitor discloses three different proteins". Biol. Chem. Hoppe-Seyler. 368 (8): 963–70. PMID 3663330.
  • Morii M, Travis J (1985). "The reactive site of human inter-alpha-trypsin inhibitor is in the amino-terminal half of the protein". Biol. Chem. Hoppe-Seyler. 366 (1): 19–21. PMID 3890890.

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