AD-36

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Template:Taxobox group i entryTemplate:Taxobox familia entryTemplate:Taxobox genus entryTemplate:Taxobox species entryTemplate:Taxobox serotype entryTemplate:Taxobox end placementTemplate:Taxobox endAD-36 is one of 51 types of adenoviruses known to infect humans. It was first shown to be associated with obesity in chickens by Dr. Nikhil Dhurandhar.[1][2] There has been a positive correlation between body fat and the presence of AD-36 antibodies in the blood[citation needed]. Previous research showed that chicken or mice injected with similar types of viruses show a statistically significant weight gain.[1] A 2.5 fold increase in fat storage was not uncommon, among the test subjects[citation needed]. There is, however, a distinctive signature of the viral weight gain, in addition to the obvious anti-bodies that can now be tested for, the weight gain is unusual in that lipids, triglycerides, and cholesterol are markedly absent, or at least very low, in the blood of the victim.[citation needed] This is distinct from normal obesity, where these chemicals are usually found in the blood in abundance, as a natural tendency in the cause and effect chain.[citation needed] Currently, no one knows where these chemicals are going, but the current hypothesis[citation needed] is that they are being stored within cells, instead of excreted via the blood stream. It was noted the following in the experiment: AD-36 has been found to increase adiposity in chickens among other non-human subjects. This is not to be mistaken for the sole, or even leading, cause of obesity if any cause at all. It is fact that this causes and increase in fat but not for any known amount of time, and certainly not for many years. Recent testing has been completed on several other human adenoviruses including AD-37 and AD-2. AD-37 showed similar correlations with the increase in fat tissue as it inducted human stem cells into fat cells.[citation needed] However, AD-37 had the reverse effect on cholesterol (increasing it) from that of AD-36. The most important discovery of these experiments (AD-36 in 2004 and AD-37 in 2007) was notes that AD-2 actually lowered the body fat in the test subjects. It is important to understand that the virus is not the only cause of obesity and that further research is needed in order to even prove that it causes any kind of long term obesity.[citation needed]

References

  1. 1.0 1.1 Dhurandhar, N V (2000). "Increased adiposity in animals due to a human virus". International Journal of Obesity. 24: 989–996. Unknown parameter |coauthors= ignored (help)
  2. Whigham, Leah D. (2006). "Adipogenic potential of multiple human adenoviruses in vivo and in vitro in animals". Am J Physiol Regul Integr Comp Physiol. 290: R190–R194. Unknown parameter |coauthors= ignored (help)

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