5-hydroxypentanoate CoA-transferase

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In enzymology, a 5-hydroxypentanoate CoA-transferase (EC is an enzyme that catalyzes the chemical reaction

acetyl-CoA + 5-hydroxypentanoate acetate + 5-hydroxypentanoyl-CoA

Thus, the two substrates of this enzyme are acetyl-CoA and 5-hydroxypentanoate, whereas its two products are acetate and 5-hydroxypentanoyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:5-hydroxypentanoate CoA-transferase. Other names in common use include 5-hydroxyvalerate CoA-transferase, and 5-hydroxyvalerate coenzyme A transferase.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Eikmanns U, Buckel W (1990). "Properties of 5-hydroxyvalerate CoA-transferase from Clostridium aminovalericum". Biol. Chem. Hoppe. Seyler. 371: 1077&ndash, 82. PMID 2085413.

External links

The CAS registry number for this enzyme class is 111684-68-5.

Gene Ontology (GO) codes