5-MeS-DMT, or 5-methylthio-N,N-dimethyltryptamine, is a lesser-known psychedelic drug. It is the 5-methylthio analog of DMT. 5-MeS-DMT was first synthesized by Alexander Shulgin. In his book TiHKAL (Tryptamines I Have Known and Loved), the minimum dosage is listed as 15-30 mg. The duration listed as very short (less then one hour), just like its analog, DMT. 5-MeS-DMT produces few effects. Shulgin describes his feelings while on this drug as “pointlessly stoned.” Very little data exists about the pharmacological properties, metabolism, and toxicity of 5-MeS-DMT.