5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase

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In enzymology, a 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase (EC 1.3.1.65) is an enzyme that catalyzes the chemical reaction

5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+ 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H+

Thus, the two substrates of this enzyme are 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline and NAD+, whereas its 3 products are 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase.

References

  • IUBMB entry for 1.3.1.65
  • BRENDA references for 1.3.1.65 (Recommended.)
  • PubMed references for 1.3.1.65
  • PubMed Central references for 1.3.1.65
  • Google Scholar references for 1.3.1.65
  • Schach S, Schwarz G, Fetzner S, Lingens F (1993). "Microbial metabolism of quinoline and related compounds. XVII Degradation of 3-methylquinoline by Comamonas testosteroni 63". Biol. Chem. Hoppe. Seyler. 374: 175&ndash, 81. PMID 8489738.

External links

Gene Ontology (GO) codes

Template:1.3-enzyme-stub


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