2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
- CTP + 2-C-methyl-D-erythritol 4-phosphate diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. This enzyme is also called MEP cytidylyltransferase. This enzyme participates in biosynthesis of steroids.
- IUBMB entry for 220.127.116.11
- BRENDA references for 18.104.22.168 (Recommended.)
- PubMed references for 22.214.171.124
- PubMed Central references for 126.96.36.199
- Google Scholar references for 188.8.131.52
- K, Eisenreich W, Bacher A, Zenk MH (1999). "Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol". Proc. Natl. Acad. Sci. U. S. A. 96: 11758&ndash, 63. PMID 10518523.
- Kuzuyama T, Takagi M, Kaneda K, Dairi T and Seto H (2000). "Formation of 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol from 2-C-methyl-D-erythritol 4-phosphate by 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, a new enzyme in the nonmevalonate pathway". Tetrahedron Lett. 41: 703&ndash, 706.
Gene Ontology (GO) codes
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