16-hydroxysteroid epimerase

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In enzymology, a 16-hydroxysteroid epimerase (EC is an enzyme that catalyzes the chemical reaction

16alpha-hydroxysteroid 16beta-hydroxysteroid

Hence, this enzyme has one substrate, 16alpha-hydroxysteroid, and one product, 16beta-hydroxysteroid.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on other compounds. The systematic name of this enzyme class is 16-hydroxysteroid 16-epimerase.


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  • Dahm K, Lindlau M, Breuer H (1968). "[Steroid epimerase--a new enzyme of estrogen metabolism]". Biochim. Biophys. Acta. 159: 377&ndash, 89. PMID 5657462.

External links

The CAS registry number for this enzyme class is 37318-40-4.

Gene Ontology (GO) codes