(R)-limonene synthase

Jump to: navigation, search

In enzymology, a (R)-limonene synthase (EC is an enzyme that catalyzes the chemical reaction

geranyl diphosphate (+)-(4R)-limonene + diphosphate

Hence, this enzyme has one substrate, geranyl diphosphate, and two products, (+)-(4R)-limonene and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming]. Other names in common use include (+)-limonene synthase, and geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming]. This enzyme participates in monoterpenoid biosynthesis.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Bouwmeester HJ, Gershenzon J, Konings MC, Croteau R (1998). "Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration Of enzyme activities and their changes with development". Plant. Physiol. 117: 901&ndash, 12. PMID 9662532.
  • Bouwmeester HJ, Verhoeven HA (2002). "Monoterpene biosynthesis in lemon (Citrus limon). cDNA isolation and functional analysis of four monoterpene synthases". Eur. J. Biochem. 269: 3160&ndash, 71. PMID 12084056.
  • Maruyama T, Ito M, Kiuchi F, Honda G (2001). "Molecular cloning, functional expression and characterization of d-limonene synthase from Schizonepeta tenuifolia". Biol. Pharm. Bull. 24: 373&ndash, 7. PMID 11305598.

External links