(+)-delta-cadinene synthase

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In enzymology, a (+)-delta-cadinene synthase (EC 4.2.3.13) is an enzyme that catalyzes the chemical reaction

2-trans,6-trans-farnesyl diphosphate (+)-delta-cadinene + diphosphate

Hence, this enzyme has one substrate, 2-trans,6-trans-farnesyl diphosphate, and two products, (+)-delta-cadinene and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming). This enzyme participates in terpenoid biosynthesis. It employs one cofactor, magnesium.

References

  • IUBMB entry for 4.2.3.13
  • BRENDA references for 4.2.3.13 (Recommended.)
  • PubMed references for 4.2.3.13
  • PubMed Central references for 4.2.3.13
  • Google Scholar references for 4.2.3.13
  • Chen XY, Chen Y, Heinstein P, Davisson VJ (1995). "Cloning, expression, and characterization of (+)-delta-cadinene synthase: a catalyst for cotton phytoalexin biosynthesis". Arch. Biochem. Biophys. 324: 255&ndash, 66. PMID 8554317.
  • Davis EM, Tsuji J, Davis GD, Pierce ML, Essenberg M (1996). "Purification of (+)-delta-cadinene synthase, a sesquiterpene cyclase from bacteria-inoculated cotton foliar tissue". Phytochemistry. 41: 1047&ndash, 55. PMID 8728715.
  • Davis GD, Essenberg M (1995). "(+)-delta-Cadinene is a product of sesquiterpene cyclase activity in cotton". Phytochemistry. 39: 553&ndash, 567.

External links

The CAS registry number for this enzyme class is 166800-09-5.

Gene Ontology (GO) codes

Template:4.2-enzyme-stub



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