Trichinosis diagnostic criteria: Difference between revisions

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{{CMG}} {{AE}} {{DL}}
{{CMG}} {{AE}} {{DL}}
==Overview==
==Overview==
The diagnosis of trichinosis is based on the European Center for Disease Control criteria, which include a combination of clinical, laboratory and epidemiological criteria.<ref name=abc>FAO/WHO/OIE Guidelines for the surveillance, management, prevention and control of trichinellosis. FAO (2007). http://www.fao.org/documents/card/en/c/61e00fb1-87e8-5b89-8be1-50481e43eed1/ Accessed on January 28, 2016  </ref><ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437  }} </ref>
The diagnosis of trichinosis is based on the European Center for Disease Control criteria, which include a combination of clinical, laboratory and epidemiological criteria.<ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437  }} </ref><ref name="abc">FAO/WHO/OIE Guidelines for the surveillance, management, prevention and control of trichinellosis. FAO (2007). http://www.fao.org/documents/card/en/c/61e00fb1-87e8-5b89-8be1-50481e43eed1/ Accessed on January 28, 2016  </ref>


==Diagnostic Criteria==
==Diagnostic Criteria==
*Clinical criteria
The following diagnostic criteria are suggested for the diagnosis of trichinosis:<ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437  }} </ref><ref name="abc">FAO/WHO/OIE Guidelines for the surveillance, management, prevention and control of trichinellosis. FAO (2007). http://www.fao.org/documents/card/en/c/61e00fb1-87e8-5b89-8be1-50481e43eed1/ Accessed on January 28, 2016  </ref>
**At least 3 of the following 6 diagnostic criteria are met:
 
***Muscle soreness and pain
=== '''Clinical criteria''' ===
***Diarrhoea
*'''At least 3 of the following 6 diagnostic criteria are met:'''
***Fever
**[[Muscle soreness|Muscle soreness and pain]]
***Facial swelling
**[[Diarrhoea|Diarrhea]]
***Subconjunctival, subungual and retinal bleeding
**[[Fever]]
***Increased eosinophils in the blood
**[[Facial edema|Facial swelling]]
*Laboratory criteria
**[[Subconjunctival haemorrhage|Subconjunctival]], subungual, and [[retinal]] [[bleeding]]
**At least 1 of the following 2 diagnostic criteria are met:
**[[Eosinophilia|Increased eosinophils in the blood]]
***Confirmation of anti-trichinella IgG by ELISA, western-blot or IFA
 
***Confirmation of trichinella larvae in muscle tissue by biopsy
=== '''Laboratory criteria''' ===
*Epidemiological criteria
*'''At least 1 of the following 2 diagnostic criteria is met:'''
**At least 1 of the following 3 diagnostic criteria are met:
**Confirmation of anti-''[[Trichinella]]'' [[IgG]] by either [[ELISA test|ELISA]], [[western blot]] or IFA, {{or}}
***Epidemiological connection to exposure of the same common source of a patient with confirmed laboratory result
**Confirmation of ''[[Trichinella]]'' larvae in muscle tissue by biopsy
***Laboratory result confirming consumption of potentially parasitised products from an infected animal
 
***Laboratory result confirming consumption of parasitised meat
=== '''Epidemiological criteria''' ===
*Confirmed case:
*'''At least 1 of the following 3 diagnostic criteria is met:'''
**Patient with clinical and laboratory criteria within the last 2 months
**Epidemiological connection to exposure of the same common source of a patient with confirmed laboratory result, {{or}}
*Possible case:
**Laboratory result confirming consumption of potentially parasitised products from an infected animal,{{or}}
**Patient with clinical and epidemiological criteria<ref name=abc>FAO/WHO/OIE Guidelines for the surveillance, management, prevention and control of trichinellosis. FAO (2007). http://www.fao.org/documents/card/en/c/61e00fb1-87e8-5b89-8be1-50481e43eed1/ Accessed on January 28, 2016  </ref><ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437  }} </ref>
**Laboratory result confirming consumption of parasitised meat
 
==Case Confirmation==
===Confirmed Case===
Patients with clinical {{and}} laboratory criteria within the last 2 months
 
===Possible Case===
Patients with clinical {{and}} epidemiological criteria
 
==References==
==References==
 
{{reflist|2}}
[[Category:Infectious disease]]

Latest revision as of 19:01, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac

Overview

The diagnosis of trichinosis is based on the European Center for Disease Control criteria, which include a combination of clinical, laboratory and epidemiological criteria.[1][2]

Diagnostic Criteria

The following diagnostic criteria are suggested for the diagnosis of trichinosis:[1][2]

Clinical criteria

Laboratory criteria

Epidemiological criteria

  • At least 1 of the following 3 diagnostic criteria is met:
    • Epidemiological connection to exposure of the same common source of a patient with confirmed laboratory result, OR
    • Laboratory result confirming consumption of potentially parasitised products from an infected animal,OR
    • Laboratory result confirming consumption of parasitised meat

Case Confirmation

Confirmed Case

Patients with clinical AND laboratory criteria within the last 2 months

Possible Case

Patients with clinical AND epidemiological criteria

References

  1. 1.0 1.1 Gottstein B, Pozio E, Nöckler K (2009). "Epidemiology, diagnosis, treatment, and control of trichinellosis". Clin Microbiol Rev. 22 (1): 127–45, Table of Contents. doi:10.1128/CMR.00026-08. PMC 2620635. PMID 19136437.
  2. 2.0 2.1 FAO/WHO/OIE Guidelines for the surveillance, management, prevention and control of trichinellosis. FAO (2007). http://www.fao.org/documents/card/en/c/61e00fb1-87e8-5b89-8be1-50481e43eed1/ Accessed on January 28, 2016