Transient ischemic attack natural history, complications and prognosis: Difference between revisions
(Created page with "__NOTOC__ {{Transient ischemic attack}} Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing. {{CMG}}...") |
Ochuko Ajari (talk | contribs) No edit summary |
||
| Line 6: | Line 6: | ||
==Complications== | ==Complications== | ||
Complications of TIA include: | |||
*Death of brain cells due to too little blood flow to the brain | *Death of brain cells due to too little blood flow to the brain | ||
*Injury that occurs from falls | *Injury that occurs from falls | ||
*[[Stroke (patient information)|Stroke]] | *[[Stroke (patient information)|Stroke]] | ||
==Prognosis== | ==Prognosis== | ||
Overall, about 10% of patients will have a stroke within 7 days.<ref name="pmid22972645">{{cite journal| author=Paul NL, Simoni M, Chandratheva A, Rothwell PM| title=Population-based study of capsular warning syndrome and prognosis after early recurrent TIA. | journal=Neurology | year= 2012 | volume= 79 | issue= 13 | pages= 1356-62 | pmid=22972645 | doi=10.1212/WNL.0b013e31826c1af8 | pmc=PMC3448742 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22972645 }} </ref> This is especially true in patients with TIA due to small-vessel disease (SVD) etiology with motor weakness (capsular warning syndrome).<ref name="pmid22972645"/> | Overall, about 10% of patients will have a stroke within 7 days.<ref name="pmid22972645">{{cite journal| author=Paul NL, Simoni M, Chandratheva A, Rothwell PM| title=Population-based study of capsular warning syndrome and prognosis after early recurrent TIA. | journal=Neurology | year= 2012 | volume= 79 | issue= 13 | pages= 1356-62 | pmid=22972645 | doi=10.1212/WNL.0b013e31826c1af8 | pmc=PMC3448742 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22972645 }} </ref> This is especially true in patients with TIA due to small-vessel disease (SVD) etiology with motor weakness (capsular warning syndrome).<ref name="pmid22972645"/> | ||
| Line 22: | Line 23: | ||
* Blood pressure at presentation ≥ 140/90 mm Hg = 1 point | * Blood pressure at presentation ≥ 140/90 mm Hg = 1 point | ||
* Clinical features | * Clinical features | ||
: | : Unilateral weakness = 2 points | ||
: | : Speech disturbance without weakness = 1 point | ||
* Duration of attack | * Duration of attack | ||
: ≥ 60 minutes = 2 points | : ≥ 60 minutes = 2 points | ||
| Line 39: | Line 40: | ||
** 2 day risk = 8.1% | ** 2 day risk = 8.1% | ||
** 7 day risk = 11.7% | ** 7 day risk = 11.7% | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Revision as of 16:57, 9 April 2013
|
Transient ischemic attack Microchapters |
|
Differentiating Transient Ischemic Attack from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Transient ischemic attack natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Transient ischemic attack natural history, complications and prognosis |
|
FDA on Transient ischemic attack natural history, complications and prognosis |
|
CDC on Transient ischemic attack natural history, complications and prognosis |
|
Transient ischemic attack natural history, complications and prognosis in the news |
|
Blogs on Transient ischemic attack natural history, complications and prognosis |
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Complications
Complications of TIA include:
- Death of brain cells due to too little blood flow to the brain
- Injury that occurs from falls
- Stroke
Prognosis
Overall, about 10% of patients will have a stroke within 7 days.[1] This is especially true in patients with TIA due to small-vessel disease (SVD) etiology with motor weakness (capsular warning syndrome).[1]
Patients diagnosed with a TIA are sometimes said to have had a warning for an approaching cerebrovascular accident. If the time period of blood supply impairment lasts more than a few minutes, the nerve cells of that area of the brain die and cause permanent neurologic deficit. One third of the people with TIA later have recurrent TIAs and one third have a stroke due to permanent nerve cell loss.
The ABCD2 score can predict likelihood of subsequent stroke.[2][3]
The score is calculated as:
- Age ≥ 60 years = 1 point
- Blood pressure at presentation ≥ 140/90 mm Hg = 1 point
- Clinical features
- Unilateral weakness = 2 points
- Speech disturbance without weakness = 1 point
- Duration of attack
- ≥ 60 minutes = 2 points
- 10–59 minutes = 1 point
- Diabetes = 1 point
Interpretation of score, the risk for stroke:
- Score 0-3 (low)
- 2 day risk = 1.0%
- 7 day risk = 1.2%
- Score 4-5 (moderate)
- 2 day risk = 4.1%
- 7 day risk = 5.9%
- Score 6–7 (high)
- 2 day risk = 8.1%
- 7 day risk = 11.7%
References
- ↑ 1.0 1.1 Paul NL, Simoni M, Chandratheva A, Rothwell PM (2012). "Population-based study of capsular warning syndrome and prognosis after early recurrent TIA". Neurology. 79 (13): 1356–62. doi:10.1212/WNL.0b013e31826c1af8. PMC 3448742. PMID 22972645.
- ↑ Johnston SC, Rothwell PM, Nguyen-Huynh MN; et al. (2007). "Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack". Lancet. 369 (9558): 283–92. doi:10.1016/S0140-6736(07)60150-0. PMID 17258668.
- ↑ Rothwell PM, Giles MF, Flossmann E; et al. (2005). "A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischaemic attack". Lancet. 366 (9479): 29–36. doi:10.1016/S0140-6736(05)66702-5. PMID 15993230.