Toxic Adenoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Patients with toxic adenomas typically present with signs and symptoms of thyrotoxicosis. Common symptoms include

History

Specific areas of focus when obtaining a history from the patient of toxic adenoma include:

• Possibility of recent iodide exposure—in the form of (can provoke transient thyrotoxicosis in a pre-existing toxic nodule)
  • Medication (e.g., amiodarone)
  • Radiocontrast dye
  • Dietary supplements

Symptoms

Patients with toxic adenomas typically present with signs and symptoms of thyrotoxicosis. Symptoms of toxic adenoma include:

• Fatigue
• Unintentional weight loss
• Heat intolerance
• Diaphoresis
• Tremor
• Palpitations
• Hyperdefecation
• Anxiety
• Nervousness
• Irritability
• Difficulty with mental concentration
• Hair loss
• Women may experience
  • Oligomenorrhea
  • Amenorrhea<ref>
• Men may complain of
  • Decrease in libido
  • Erectile dysfunction
  • Gynecomastia<ref>

Signs of thyrotoxicosis

• Tachycardia
• Systolic hypertension
• Hyperactive or fatigued demeanor
• Staring gaze and lag
• Brisk carotid upstrokes
• Hyperdynamic point of maximal impulse
• Systolic flow murmur
• Proximal muscle weakness
• Fine hand tremor
• Velvety or oily skin
• Hair thinning.