Sandbox: HCL
Laboratory Findings
Complete Blood Count
- Decreased hemoglobin concentration[1]
- Decreased platelets count
- Decreased WBC count
Blood Smear
Metabolic Panel
- Elevated low-density lipoprotein level[1][2]
Quantitative Immunoglobulin Assay
- Quantitative measurement of IgA, IgG, and IgM immunoglobulins to detect hypogammaglobulinemia[1][2]
- Elevated β2-microglobulin level
Electrophoresis
- Monoclonality of kappa and lambda producing B cells is a key diagnostic feature among patients with chronic lymphocytic leukemia.[1][2]
Immunohistochemistry
- Chronic lymphocytic leukemia cells typically express CD19, CD20, CD23, and CD5 on the cell surface.[1][2]
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Wadhwa RK, McKenzie R (1972). "Complications of band-aid surgery for sterilization". JAMA. 222 (12): 1558. PMID 4264273.
- ↑ 2.0 2.1 2.2 2.3 2.4 Chronic Lymphocytic Leukimea. Wikipedia (2015) https://en.wikipedia.org/wiki/B-cell_chronic_lymphocytic_leukemia Accessed on October ,12 2015