Rash with fever: Difference between revisions

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| [[File:Siren.gif|30px|link=Rash with fever resident survival guide]]|| <br> || <br>
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| [[Rash with fever resident survival guide|'''Resident'''<br>'''Survival'''<br>'''Guide''']]
|[[Rash with fever resident survival guide|'''Resident'''<br>'''Survival'''<br>'''Guide''']]
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{{Search infobox}}
{{Search infobox}}
{{CMG}}
{{CMG}}
==Overview==
==Overview==
Rash with Fever in adults can be caused by allergic reactions, Immune disorders, infections, etc.<ref name="pmid30981291">{{cite journal| author=Muzumdar S, Rothe MJ, Grant-Kels JM| title=The rash with maculopapules and fever in adults. | journal=Clin Dermatol | year= 2019 | volume= 37 | issue= 2 | pages= 109-118 | pmid=30981291 | doi=10.1016/j.clindermatol.2018.12.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30981291  }} </ref> <ref name="pmid23197907">{{cite journal| author=Tabak F, Murtezaoglu A, Tabak O, Ozaras R, Mete B, Kutlubay Z | display-authors=etal| title=Clinical features and etiology of adult patients with Fever and rash. | journal=Ann Dermatol | year= 2012 | volume= 24 | issue= 4 | pages= 420-5 | pmid=23197907 | doi=10.5021/ad.2012.24.4.420 | pmc=3505772 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23197907  }} </ref>. The infectious agents often trigger rash by mode of a toxin or an immunogenic reaction to the antigens. Infectious agents associated with fever with rash in adults can be viral or bacterial. Some examples of such organisms are the Rubeola virus, Staphylococcus aureus, Borrelia burgdorferi. Among allergic reactions, drugs reactions are the ones most commonly associated with Rash with Fever.  
[[Rash]] with [[Fever]] in adults can be caused by [[allergic reactions]], [[Immune disorders]], [[infections]], etc.<ref name="pmid30981291">{{cite journal| author=Muzumdar S, Rothe MJ, Grant-Kels JM| title=The rash with maculopapules and fever in adults. | journal=Clin Dermatol | year= 2019 | volume= 37 | issue= 2 | pages= 109-118 | pmid=30981291 | doi=10.1016/j.clindermatol.2018.12.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30981291  }} </ref> <ref name="pmid23197907">{{cite journal| author=Tabak F, Murtezaoglu A, Tabak O, Ozaras R, Mete B, Kutlubay Z | display-authors=etal| title=Clinical features and etiology of adult patients with Fever and rash. | journal=Ann Dermatol | year= 2012 | volume= 24 | issue= 4 | pages= 420-5 | pmid=23197907 | doi=10.5021/ad.2012.24.4.420 | pmc=3505772 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23197907  }} </ref>. The infectious agents often trigger rash by mode of a [[toxin]] or an [[Immune reaction|immunogenic reaction]] to the [[antigens]]. Infectious agents associated with fever with rash in adults can be [[Viruses|viral]] or [[Bacteria|bacterial]]. Some examples of such organisms are the [[Rubeola]] virus, [[Staphylococcus aureus]], [[Borrelia burgdorferi]]. Among allergic reactions, drugs reactions are the ones most commonly associated with Rash with Fever. The clinical condition of the patient can range from mild flu-like symptoms in [[Lyme's disease]] to severe life-threatening situations such as [[Toxic shock syndrome]] caused by Staphylococcus aureus.     
The clinical condition of the patient can range from mild flu-like symptoms in Lyme's disease to severe life-threatening situations such as Toxic shock syndrome caused by Staphylococcus aureus.     


==Causes==  
==Causes==  
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===Life threatening causes===
===Life threatening causes===


* Toxic Shock syndrome caused by Staphcocci or Streptococci
*[[Toxic shock syndrome|Toxic Shock syndrome]] caused by Staphcocci or Streptococci
* Staphylococcal Scalded Skin Syndrome causes by Staphylococcus aureus
*[[Staphylococcal Scalded Skin Syndrome]] causes by [[Staphylococcus aureus]]
* Toxic Epidermal Necrolysis-Steven Johnson syndrome (TEN-SJS)
*[[Toxic Epidermal Necrolysis|Toxic Epidermal Necrolysis-Steven Johnson syndrome]] (TEN-SJS)
* Acute meningococcemia by Neisseria Meningitidis
*[[Acute meningococcemia]] by [[Neisseria Meningitidis]]


===Common causes===
===Common causes===
* Measles/ Rubeola
 
* Drugs reactions
*[[Measles|Measles/ Rubeola]]
* Infectious Mononucleosis
*Drugs reactions
* Adult-onset Stills disease
*[[Infectious Mononucleosis]]
* West Nile Fever
*Adult-onset Stills disease
* Rickettsial infections such as Lyme disease, Rocky Mountain spotted fever
*[[West Nile Fever]]
* Systemic Lupus Erythematosus
*Rickettsial infections such as [[Lyme disease]], [[Rocky Mountain spotted fever]]
*[[Systemic Lupus Erythematosus (SLE)|Systemic Lupus Erythematosus]]


===Less common causes===
===Less common causes===
* Typhoid fever
 
* Dengue fever
*[[Typhoid fever]]
* Parvovirus B19
*[[Dengue fever]]
* Acute HIV infection
*[[Parvovirus B19]]
* Graft vs Host reaction
*[[HIV AIDS|Acute HIV infection]]
* Dermatomyositis
*[[Graft vs Host reaction]]
* Pyoderma gangrenosum
*[[Dermatomyositis]]
* Sweet Syndrome
*[[Pyoderma gangrenosum]]
*[[Sweet's syndrome|Sweet Syndrome]]


===Causes by Organ system===
===Causes by Organ system===
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{| style="width:80%; height:100px" border="1"
{| style="width:80%; height:100px" border="1"
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
| style="width:75%" bgcolor="Beige" ; border="1" | No underlying causes
| style="width:75%" bgcolor="Beige" ; border="1" |No underlying causes
|-
|-
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning'''
| bgcolor="LightSteelBlue" |'''Chemical/Poisoning'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dental'''
|'''Dental'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dermatologic'''
|'''Dermatologic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|'''Drug Side Effect'''
| bgcolor="Beige" | Toxic Epidermal Necrolysis; Drug eruptions; Steven Johnson syndrome
| bgcolor="Beige" |Toxic Epidermal Necrolysis; Drug eruptions; Steven Johnson syndrome
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|'''Ear Nose Throat'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Endocrine'''
|'''Endocrine'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Environmental'''
|'''Environmental'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|'''Gastroenterologic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Genetic'''  
|'''Genetic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Hematologic'''
|'''Hematologic'''
| bgcolor="Beige" | Lymphoma
| bgcolor="Beige" |Lymphoma
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|'''Iatrogenic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|'''Infectious Disease'''
| bgcolor="Beige" | Various viral and bacterial agents eg Zika, Dengue, Roseola, Typhoid, Parvovirus B19, Meningococci, Staphylococci  
| bgcolor="Beige" |Various viral and bacterial agents eg Zika, Dengue, Roseola, Typhoid, Parvovirus B19, Meningococci, Staphylococci
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|'''Musculoskeletal/Orthopedic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Neurologic'''
|'''Neurologic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|'''Nutritional/Metabolic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|'''Obstetric/Gynecologic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Oncologic'''
|'''Oncologic'''
| bgcolor="Beige" | Paraneoplastic syndrome
| bgcolor="Beige" |Paraneoplastic syndrome
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|'''Ophthalmologic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|'''Overdose/Toxicity'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Psychiatric'''
|'''Psychiatric'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Pulmonary'''
|'''Pulmonary'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|'''Renal/Electrolyte'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|'''Rheumatology/Immunology/Allergy'''
| bgcolor="Beige" | SLE; Adult-Onset Still's disease; Dermatomyositis  
| bgcolor="Beige" |SLE; Adult-Onset Still's disease; Dermatomyositis
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Sexual'''
|'''Sexual'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Trauma'''
|'''Trauma'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Urologic'''
|'''Urologic'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|- bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|'''Miscellaneous'''
| bgcolor="Beige" | No underlying causes
| bgcolor="Beige" |No underlying causes
|-
|-
|}
|}

Revision as of 15:22, 17 December 2020
Resident
Survival
Guide

Template:Search infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Rash with Fever in adults can be caused by allergic reactions, Immune disorders, infections, etc.[1] [2]. The infectious agents often trigger rash by mode of a toxin or an immunogenic reaction to the antigens. Infectious agents associated with fever with rash in adults can be viral or bacterial. Some examples of such organisms are the Rubeola virus, Staphylococcus aureus, Borrelia burgdorferi. Among allergic reactions, drugs reactions are the ones most commonly associated with Rash with Fever. The clinical condition of the patient can range from mild flu-like symptoms in Lyme's disease to severe life-threatening situations such as Toxic shock syndrome caused by Staphylococcus aureus.

Causes

Life threatening causes

Common causes

Less common causes

Causes by Organ system

Cardiovascular No underlying causes
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Toxic Epidermal Necrolysis; Drug eruptions; Steven Johnson syndrome
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic Lymphoma
Iatrogenic No underlying causes
Infectious Disease Various viral and bacterial agents eg Zika, Dengue, Roseola, Typhoid, Parvovirus B19, Meningococci, Staphylococci
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Paraneoplastic syndrome
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy SLE; Adult-Onset Still's disease; Dermatomyositis
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes


Causes in Alphabetical Order[3][4]

References

  1. ↑ Muzumdar S, Rothe MJ, Grant-Kels JM (2019). "The rash with maculopapules and fever in adults". Clin Dermatol. 37 (2): 109–118. doi:10.1016/j.clindermatol.2018.12.004. PMID 30981291.
  2. ↑ Tabak F, Murtezaoglu A, Tabak O, Ozaras R, Mete B, Kutlubay Z; et al. (2012). "Clinical features and etiology of adult patients with Fever and rash". Ann Dermatol. 24 (4): 420–5. doi:10.5021/ad.2012.24.4.420. PMC 3505772. PMID 23197907.
  3. ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  4. ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X


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