Polycythemia vera CT: Difference between revisions
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{{Polycythemia vera}} | {{Polycythemia vera}} | ||
{{CMG}} {{AE}} {{MJK}} {{shyam}} | {{CMG}} {{AE}} {{MJK}}; {{shyam}} | ||
==Overview== | ==Overview== | ||
Abdominal and chest [[CT scan]] may be helpful in the diagnosis of polycythemia vera. Findings on CT scan suggestive of polycythemia vera include enlarged lymph nodes, [[splenomegaly]], and splanchnic venous thrombosis. | Abdominal and chest [[CT scan]] may be helpful in the diagnosis of polycythemia vera. Findings on CT scan suggestive of polycythemia vera include enlarged lymph nodes, [[splenomegaly]], and splanchnic venous thrombosis. | ||
Revision as of 16:19, 22 February 2018
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Polycythemia vera Microchapters |
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Polycythemia vera CT On the Web |
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American Roentgen Ray Society Images of Polycythemia vera CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]; Shyam Patel [3]
Overview
Abdominal and chest CT scan may be helpful in the diagnosis of polycythemia vera. Findings on CT scan suggestive of polycythemia vera include enlarged lymph nodes, splenomegaly, and splanchnic venous thrombosis.
CT
CT plays a significant role in the further assessment of polycythemia vera and its complications.[1][2] CT can assist with detection of:
- Lymphadenopathy: Malignant hematologic disease is commonly associated with enlargement of lymph nodes. CT can quantify the degree of lymphadenopathy and can accurate measure lymph node size.
- Splenomegaly: Enlargement of the spleen is frequently found in patients with polycythemia vera, as extramedullary hematopoiesis occurs in the spleen. CT can quantitate spleen size, and serial CTs are sometimes useful for assessment of interval changes in clinical condition. CT of the abdomen is more sensitive that abdominal ultrasound for detection of splenomegaly, although the cost of CT is higher and there is a risk for radiation-induced cancers.
- Hepatomegaly: CT can quantitate liver size. This is sometimes useful in patients with polycythemia vera and other myeloproliferative neoplasms.
- Splanchnic venous thrombosis: Patients with polycythemia vera can develop thromboses at unusual sites, including mesenteric vasculature such as the portal vein, superior mesenteric vein, and inferior mesenteric vein.
- Pulmonary embolism: CT angiography of the chest is the optimal test for assessment for thrombosis of the pulmonary vasculature. Venous thromboembolism events are common in patients with high-risk polycythemia vera.
References
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/diagnosis/?region=ab
- ↑ Lim BK (2013). "Clinics in diagnostic imaging (146). Polycythaemia vera (PV)". Singapore Med J. 54 (5): 289–91, quiz 292. PMID 23716157.