Pharyngitis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]

Overview

Testing for pharyngitis usually is not recommended for children or adults with acute pharyngitis with clinical and epidemiological features that strongly suggest a viral etiology (eg, cough, rhinorrhea, hoarseness, and oral ulcers).[1] Diagnostic studies for GAS are not indicated for children <3 years old because acute rheumatic fever is rare in children <3 years old and the incidence of streptococcal pharyngitis and the classic presentation of streptococcal pharyngitis are uncommon in this age group. Selected children <3 years old who have other risk factors, such as an older sibling with GAS infection, may be considered for testing.[1]

Laboratory Findings

Viral Etiology

Bacterial Etiology

Group A streptococcus: No single element in the history or physical examination is sensitive or specific enough to exclude or diagnose strep throat.[2]

Diphtheria: The diagnosis, which may be strongly suspected on epidemiologic and clinical grounds, should be confirmed by culture of the pseudomembrane in Loeffler’s or tellurite selective medium.[3]

Neisseria gonorrhoeae: The diagnosis should be confirmed by culture on Thayer–Martin medium.[3]

Reference

  1. 1.0 1.1 Shulman ST, Bisno AL, Clegg HW, Gerber MA, Kaplan EL, Lee G et al. (2012) Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis 55 (10):1279-82. DOI:10.1093/cid/cis847 PMID: 23091044
  2. Vincent MT, Celestin N, Hussain AN (2004) Pharyngitis. Am Fam Physician 69 (6):1465-70. PMID: 15053411
  3. 3.0 3.1 Bisno AL (2001) Acute pharyngitis. N Engl J Med 344 (3):205-11. DOI:10.1056/NEJM200101183440308 PMID: 11172144

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