Pathophysiology template

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Introduction to the Pathophysiology Page

The pathophysiology of disease involves the study of the biological and physical manifestations of a disease, as they correlate with the underlying abnormalities and physiological disturbances.
Goal: to explain the biological mechanisms underlying the disease state.
Appropriate content: A description of the abnormalities at a cellular and molecular level, the abnormalities at a gross and functional level, and the causative factor in the disease process. The description can also include a description of the genetic abnormalities, embryological and developmental abnormalities, pathogenesis, and pathology images.
The individual sections, with a brief description and example of each is outlined below.

The overview section should include the disease name in the first sentence.
The goal is to summarize the page several sentences, and the section can be the same as the pathophysiology segment on the overview page.
To see an example, click here

The disease may be able to be classified at a pathological level based on its manifestations or appearance.
Classification may include the genus and species of the bacteria/ viruses/ protozoa causing certain variants of infectious disease.
For an example of a section on classification, click here.

Pathogenesis is the mechanism by which a certain factor causes disease (pathos = disease, genesis = development). The term can also be used to describe the development of the disease, whether it is acute, chronic, recurrent etc.
This section should include the name of the disease in the first sentence.

Some forms of pathogenesis are inflammation, malignancy, necrosis etc.

For an example of a pathogenesis section within a pathophysiology page, click here

Gross pathology refers to macroscopic or larger scale manifestations of disease in organs, tissues and body cavities. The term is commonly used by pathologist to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy.
This section is a good place to include pictures. Search for copyleft images on The Pathology Wiki [2] and Ask Dr. Wiki [3].
For an example of this section, click here.

Microscopic pathology is the disease process as it occurs at the micrscopic level.
- This section is a good place to include pictures. Search for copyleft images on The Pathology Wiki [4] and Ask Dr. Wiki [5].
For an example of this section, click here.