Odynophagia pathophysiology: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 13: Line 13:
* The motor and most of the sensory supply to the pharynx is by way of the pharyngeal plexus, which, situated chiefly on the middle constrictor, is formed by the pharyngeal branches of the vagus and glossopharyngeal nerves and also by sympathetic nerve fibers.<ref name="pmid29310398">{{cite journal| author=Li X, Wang Y, Wang F, Li B, Sun S, Yang H| title=An unusual case of oropharyngeal chordoma: A case report and literature review. | journal=Medicine (Baltimore) | year= 2017 | volume= 96 | issue= 48 | pages= e8963 | pmid=29310398 | doi=10.1097/MD.0000000000008963 | pmc=5728799 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29310398  }} </ref>
* The motor and most of the sensory supply to the pharynx is by way of the pharyngeal plexus, which, situated chiefly on the middle constrictor, is formed by the pharyngeal branches of the vagus and glossopharyngeal nerves and also by sympathetic nerve fibers.<ref name="pmid29310398">{{cite journal| author=Li X, Wang Y, Wang F, Li B, Sun S, Yang H| title=An unusual case of oropharyngeal chordoma: A case report and literature review. | journal=Medicine (Baltimore) | year= 2017 | volume= 96 | issue= 48 | pages= e8963 | pmid=29310398 | doi=10.1097/MD.0000000000008963 | pmc=5728799 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29310398  }} </ref>
* The motor fibers in the plexus are carried by the vagus (although they likely represent cranial accessory nerve components) and supply all the muscles of the pharynx and soft palate except the stylopharyngeus (supplied by cranial nerve IX) and tensor veli palatini (supplied by cranial nerve V).
* The motor fibers in the plexus are carried by the vagus (although they likely represent cranial accessory nerve components) and supply all the muscles of the pharynx and soft palate except the stylopharyngeus (supplied by cranial nerve IX) and tensor veli palatini (supplied by cranial nerve V).
* The sensory fibers in the plexus are from the glossopharyngeal nerve, and they supply the greater portion of all three parts of the pharynx. 
* The sensory fibers in the plexus are from the glossopharyngeal nerve, and they supply the greater portion of all three parts of the pharynx. <ref name="pmid29245445">{{cite journal| author=Negrete L, Brusa F| title=Increasing diversity of land planarians (Platyhelminthes: Geoplanidae) in the Interior Atlantic Forest with the description of two new species and new records from Argentina. | journal=Zootaxa | year= 2017 | volume= 4362 | issue= 1 | pages= 99-127 | pmid=29245445 | doi=10.11646/zootaxa.4362.1.5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29245445  }}</ref>
* The pharynx is supplied by branches of the external carotid (ascending pharyngeal) and subclavian (inferior thyroid) arteries.
* The pharynx is supplied by branches of the external carotid (ascending pharyngeal) and subclavian (inferior thyroid) arteries.
* The motor and most of the sensory supply to the pharynx is by way of the pharyngeal plexus.
* The motor and most of the sensory supply to the pharynx is by way of the pharyngeal plexus.
* Pharyngeal plexus is formed by the pharyngeal branches of the vagus and glossopharyngeal nerves and also by sympathetic nerve fibers.
* Pharyngeal plexus is formed by the pharyngeal branches of the vagus and glossopharyngeal nerves and also by sympathetic nerve fibers.
* The motor fibers in the plexus are carried by the vagus (although they likely represent cranial accessory nerve components) and supply all the muscles of the pharynx and soft palate except the stylopharyngeus (supplied by cranial nerve IX) and tensor veli palatini (supplied by cranial nerve V).
* The motor fibers in the plexus are carried by the vagus (although they likely represent cranial accessory nerve components) and supply all the muscles of the pharynx and soft palate except the stylopharyngeus (supplied by cranial nerve IX) and tensor veli palatini (supplied by cranial nerve V).
* The sensory fibers in the plexus are from the glossopharyngeal nerve, and they supply the greater portion of all three parts of the pharynx. The pharynx is supplied by branches of the external carotid (ascending pharyngeal) and subclavian (inferior thyroid) arteries.
* The sensory fibers in the plexus are from the glossopharyngeal nerve, and they supply the greater portion of all three parts of the pharynx. The pharynx is supplied by branches of the external carotid (ascending pharyngeal) and subclavian (inferior thyroid) arteries.<ref name="pmid29224765">{{cite journal| author=Lai D, Qin G, Pu J, Liu L, Yang Y| title=Pre- and post-operative application of acoustic rhinometry in children with otitis media with effusion and with or without adenoid hypertrophy-a retrospective analysis. | journal=Int J Pediatr Otorhinolaryngol | year= 2017 | volume= 103 | issue=  | pages= 51-54 | pmid=29224765 | doi=10.1016/j.ijporl.2017.10.009 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29224765  }}</ref>
* The esophagus, like the rest of the viscera, receives dual sensory innervation, traditionally referred to as parasympathetic and sympathetic, but more properly based on the actual nerves, vagal, and spinal.
* The esophagus, like the rest of the viscera, receives dual sensory innervation, traditionally referred to as parasympathetic and sympathetic, but more properly based on the actual nerves, vagal, and spinal.<ref name="pmid29287649">{{cite journal| author=Irani SK, Oliver DR, Movahed R, Kim YI, Thiesen G, Kim KB| title=Pharyngeal airway evaluation after isolated mandibular setback surgery using cone-beam computed tomography. | journal=Am J Orthod Dentofacial Orthop | year= 2018 | volume= 153 | issue= 1 | pages= 46-53 | pmid=29287649 | doi=10.1016/j.ajodo.2017.05.031 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29287649  }}</ref>


====== Pathological conditions causing pain in swallowing: ======
====== Pathological conditions causing pain in swallowing: ======

Revision as of 14:38, 5 February 2018

Odynophagia Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Odynophagia from other Conditions

Epidemiology and Demographics

Screening

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Odynophagia pathophysiology On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Odynophagia pathophysiology

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Odynophagia pathophysiology

CDC on Odynophagia pathophysiology

Odynophagia pathophysiology in the news

Blogs on Odynophagia pathophysiology

Directions to Hospitals Treating Odynophagia

Risk calculators and risk factors for Odynophagia pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]

Odynophagia pathophysiology is related to causes.Following are common mechanisms involved in inducing pain in esophagus and pharynx

Anatomic facts of pharynx and esophagus:
  • Pharynx is divided in to into three sections: the nasopharynx, the oropharynx and the laryngopharynx. Odynophagia is due to painful stimuli of orophyranx and laryngopharynx.[1]
  • The oropharynx lies behind the oral cavity, extending from the uvula to the level of the hyoid bone. It opens anteriorly, through the isthmus faucium, into the mouth, while in its lateral wall, between the palatoglossal arch and the palatopharyngeal arch, is the palatine tonsil. 
  • The oropharynx is lined by non-keratinised squamous stratified epithelium.[2]
  • The laryngopharynx, (Latin: pars laryngea pharyngis), also known as hypopharynx, is the caudal part of pharynx; it is the part of the throat that connects to the esophagus.
  • The mucosa of the larynx is supplied on each side chiefly by the internal laryngeal branch of the superior laryngeal nerve, which supplies the larynx as far down as the vocal folds. The inferior part of the larynx receives sensory fibers from the recurrent laryngeal nerve.
  • The motor and most of the sensory supply to the pharynx is by way of the pharyngeal plexus, which, situated chiefly on the middle constrictor, is formed by the pharyngeal branches of the vagus and glossopharyngeal nerves and also by sympathetic nerve fibers.[3]
  • The motor fibers in the plexus are carried by the vagus (although they likely represent cranial accessory nerve components) and supply all the muscles of the pharynx and soft palate except the stylopharyngeus (supplied by cranial nerve IX) and tensor veli palatini (supplied by cranial nerve V).
  • The sensory fibers in the plexus are from the glossopharyngeal nerve, and they supply the greater portion of all three parts of the pharynx. [4]
  • The pharynx is supplied by branches of the external carotid (ascending pharyngeal) and subclavian (inferior thyroid) arteries.
  • The motor and most of the sensory supply to the pharynx is by way of the pharyngeal plexus.
  • Pharyngeal plexus is formed by the pharyngeal branches of the vagus and glossopharyngeal nerves and also by sympathetic nerve fibers.
  • The motor fibers in the plexus are carried by the vagus (although they likely represent cranial accessory nerve components) and supply all the muscles of the pharynx and soft palate except the stylopharyngeus (supplied by cranial nerve IX) and tensor veli palatini (supplied by cranial nerve V).
  • The sensory fibers in the plexus are from the glossopharyngeal nerve, and they supply the greater portion of all three parts of the pharynx. The pharynx is supplied by branches of the external carotid (ascending pharyngeal) and subclavian (inferior thyroid) arteries.[5]
  • The esophagus, like the rest of the viscera, receives dual sensory innervation, traditionally referred to as parasympathetic and sympathetic, but more properly based on the actual nerves, vagal, and spinal.[6]
Pathological conditions causing pain in swallowing:

Infections:

Infection of esophagus or pharynx causes fluid leaking in interstitial media of mucous epithelium and it produce pressure on sensory nerve terminals situated in mucousa.

Tumors:

It produce pain due to compression effect of mass on sensory nerve terminals situated in mucousa.

Foreign body:

It produce pain due to compression effect of foreign body on sensory nerve terminals situated in mucousa.

References

  1. Isono S, Remmers JE, Tanaka A, Sho Y, Sato J, Nishino T (1997). "Anatomy of pharynx in patients with obstructive sleep apnea and in normal subjects". J Appl Physiol (1985). 82 (4): 1319–26. doi:10.1152/jappl.1997.82.4.1319. PMID 9104871.
  2. Schubert FR, Singh AJ, Afoyalan O, Kioussi C, Dietrich S (2018). "To roll the eyes and snap a bite - function, development and evolution of craniofacial muscles". Semin Cell Dev Biol. doi:10.1016/j.semcdb.2017.12.013. PMID 29331210.
  3. Li X, Wang Y, Wang F, Li B, Sun S, Yang H (2017). "An unusual case of oropharyngeal chordoma: A case report and literature review". Medicine (Baltimore). 96 (48): e8963. doi:10.1097/MD.0000000000008963. PMC 5728799. PMID 29310398.
  4. Negrete L, Brusa F (2017). "Increasing diversity of land planarians (Platyhelminthes: Geoplanidae) in the Interior Atlantic Forest with the description of two new species and new records from Argentina". Zootaxa. 4362 (1): 99–127. doi:10.11646/zootaxa.4362.1.5. PMID 29245445.
  5. Lai D, Qin G, Pu J, Liu L, Yang Y (2017). "Pre- and post-operative application of acoustic rhinometry in children with otitis media with effusion and with or without adenoid hypertrophy-a retrospective analysis". Int J Pediatr Otorhinolaryngol. 103: 51–54. doi:10.1016/j.ijporl.2017.10.009. PMID 29224765.
  6. Irani SK, Oliver DR, Movahed R, Kim YI, Thiesen G, Kim KB (2018). "Pharyngeal airway evaluation after isolated mandibular setback surgery using cone-beam computed tomography". Am J Orthod Dentofacial Orthop. 153 (1): 46–53. doi:10.1016/j.ajodo.2017.05.031. PMID 29287649.

Template:WH Template:WS