Non-alcoholic fatty liver disease epidemiology and demographics

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Editor in Chief: Elliot Tapper, M.D., Beth Israel Deaconess Medical Center, C. Michael Gibson, M.S., M.D. [1]

Overview

In the third National Health and Nutrition Examination Survey (NHANES III), the peak prevalence of NAFLD in men occurred in the fourth decade and in the sixth decade for women.NAFLD is associated with visceral obesity and diabetes. It has mirrored the epidemiologic course of obesity in the US and is detected in 73–90% of obese individuals on biopsy. Approximately 1/3 of the usa population are estimated to have NAFL. Through most estimates, NASH accommodates approximately 15% of all NAFLD and 3–5% of the american populace.

Epidemiology and Demographics

Epidemiology

NAFLD is associated with visceral obesity and diabetes. It has reflected the epidemiologic direction of weight problems inside the US and is detected in 73–90% of obese people on biopsy.about 1/3 of america population are expected to have NAFL. with the aid of maximum estimates, NASH contains about 15% of all NAFLD and 3–5% of the american populace. Hospitalizations for NAFLD have elevated by means of 97%.[1]

Prevalance

  • As the prevalence of fatty liver ailment increases, clinicians can have greater equipment at hand for control of this condition. We conclude the horizon is vibrant for sufferers and docs who address NAFLD.[2]

Ethinicity

As a part of the Dallas Heart Study,[3] 2,240 patients - 1,105 african-americans, 401 hispanics and 734 caucasians - received abdominal MRI's from which we can infer the presence of steatosis. Hepatic steatosis was found in 45% of hispanics (both men and women), 33% of caucasians (42% of men, 24% of women) and 24% of african-american (23% of men, 24% of women). This pattern may hold true in children as well. In a San Diego study of 742 consecutive autopsies of children victims of trauma over 10 years, fatty liver was found in 9.6% of all children, 38% of the obese, 12% of hispanics, 10% of asians, 8.6% of caucasians and 1.5% of african-americans.[4]

References

  1. Vizuete J, Camero A, Malakouti M, Garapati K, Gutierrez J (2017). "Perspectives on Nonalcoholic Fatty Liver Disease: An Overview of Present and Future Therapies". J Clin Transl Hepatol. 5 (1): 67–75. doi:10.14218/JCTH.2016.00061. PMC 5411359. PMID 28507929.
  2. Vizuete J, Camero A, Malakouti M, Garapati K, Gutierrez J (2017). "Perspectives on Nonalcoholic Fatty Liver Disease: An Overview of Present and Future Therapies". J Clin Transl Hepatol. 5 (1): 67–75. doi:10.14218/JCTH.2016.00061. PMC 5411359. PMID 28507929.
  3. Browning et al. Prevalence of Hepatic Steatosis in an Urban Population in the United States: Impact of Ethnicity. Hepatology 2004;40:1387-1395.
  4. Schwimmer et al. Prevalence of fatty liver in children and adolescents. Pediatrics 2006;118;1388-93.

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