Non-alcoholic fatty liver disease ultrasound

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Ultrasound may be helpful in the diagnosis of non-alcoholic fatty liver disease. Increased echogenicity and coarsened echotexture of the liver is the most prominent and diagnostic finding on an ultrasound in patients diagnosed non-alcoholic fatty liver disease.

Ultrasound

  • Ultrasound is considered as the first line of imaging choice for NAFLD patients
  • Ultrasound have senstivity of 60-100 and 80-100 % of positive predictive value.
  • Findings on an ultrasound suggestive of non-alcoholic fatty liver disease include:
    • Moderate to high amount of fatty infiltration of liver which is reflected as increased echogenicity and coarsened echotexture of the liver.
    • If steato-hepatitis has progressed to cirrhosis, a nodular liver surface may be present in addition to other fibrotic changes.[1]
  • Ultrasound elastography is another kind of ultrasound that can give qualitative progression of the liver fibrosis.
  • The only limitation of using an ultrasound is that it cannot differentiate between hepatic fibrosis and steatosis.

References

  1. Lee DH (2017). "Imaging evaluation of non-alcoholic fatty liver disease: focused on quantification". Clin Mol Hepatol. doi:10.3350/cmh.2017.0042. PMID 28994271.

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