Nasopharyngeal carcinoma natural history, complications and prognosis: Difference between revisions
| Line 26: | Line 26: | ||
* Spread of the cancer to other body areas ([[metastasis]]) | * Spread of the cancer to other body areas ([[metastasis]]) | ||
Potential complications of [[radiotherapy]] include: | |||
*[[Radiation]] necrosis of the [[temporal lobes]] | *[[Radiation]] necrosis of the [[temporal lobes]] | ||
*[[Cranial]] nerve dysfunction | *[[Cranial]] nerve dysfunction | ||
*[[Atrophy]] and fibrosis of the [[muscles of mastication]] | *[[Atrophy]] and fibrosis of the [[muscles of mastication]] | ||
Revision as of 20:39, 17 September 2015
|
Nasopharyngeal carcinoma Microchapters |
|
Differentiating Nasopharyngeal carcinoma from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Nasopharyngeal carcinoma natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Nasopharyngeal carcinoma natural history, complications and prognosis |
|
FDA on Nasopharyngeal carcinoma natural history, complications and prognosis |
|
CDC on Nasopharyngeal carcinoma natural history, complications and prognosis |
|
Nasopharyngeal carcinoma natural history, complications and prognosis in the news |
|
Blogs on Nasopharyngeal carcinoma natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
If left untreated nasopharyngeal carcinoma produces few symptoms early in course. Non-keratinizing nasopharyngeal carcinoma is associated with a 5 year survival rate of 65%. The common complications of nasopharyngeal carcinoma include airway obstruction, dysphagia and disfigurement of the neck or face.
Natural history
If left untreated nasopharyngeal carcinoma produces few symptoms early in its course. Once the tumor has expanded from its site of origin in the lateral wall of the nasopharynx, it may obstruct the nasal passages and cause nasal discharge or epistaxis.
Prognosis
Non-keratinizing nasopharyngeal carcinoma is associated with a 5 year survival rate of 65%. [1] Prognosis is influenced both by stage and tumour type:
- Type I: Keratinizing squamous cell carcinoma - 42% 5-year survival
- Type II: Non-keratinizing squamous cell carcinoma - 65% 5-year survival
- Type III: Undifferentiated carcinoma - 14% 5-year survival[2]
Complications
Complications of nasopharyngeal carcinoma include:
- Airway obstruction
- Difficulty swallowing
- Disfigurement of the neck or face
- Hardening of the skin of the neck
- Loss of voice and speaking ability
- Spread of the cancer to other body areas (metastasis)
Potential complications of radiotherapy include:
- Radiation necrosis of the temporal lobes
- Cranial nerve dysfunction
- Atrophy and fibrosis of the muscles of mastication
References
- ↑ Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor). Modern Surgical Pathology (2 Volume Set). London: W B Saunders. ISBN 0-7216-7253-1.
- ↑ http://radiopaedia.org/articles/nasopharyngeal-carcinoma